URI1 (URI1 prefoldin like chaperone)

2011-06-01  

Identity

HGNC
URI1
LOCATION
19q12
LOCUSID
8725
ALIAS
C19orf2,NNX3,PPP1R19,RMP,URI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8725
MIM: 603494
HGNC: 13236
Ensembl: ENSG00000105176

Variants:

dbSNP: 8725
ClinVar: 8725
TCGA: ENSG00000105176
COSMIC: URI1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105176ENST00000360605O94763
ENSG00000105176ENST00000392271O94763
ENSG00000105176ENST00000570564I3L2V7
ENSG00000105176ENST00000573052I3L0K5
ENSG00000105176ENST00000574110I3L467
ENSG00000105176ENST00000574233I3L104
ENSG00000105176ENST00000574666I3L130
ENSG00000105176ENST00000575242I3L280
ENSG00000105176ENST00000576442I3NI51
ENSG00000105176ENST00000585655K7EQZ9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
344213522021URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells.4
344213522021URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells.4
317395772019HBx and c-MYC Cooperate to Induce URI1 Expression in HBV-Related Hepatocellular Carcinoma.6
317395772019HBx and c-MYC Cooperate to Induce URI1 Expression in HBV-Related Hepatocellular Carcinoma.6
275825472017Detection of CCNE1/URI (19q12) amplification by in situ hybridisation is common in high grade and type II endometrial cancer.8
284237372017RMP promotes epithelial-mesenchymal transition through NF-κB/CSN2/Snail pathway in hepatocellular carcinoma.9
275825472017Detection of CCNE1/URI (19q12) amplification by in situ hybridisation is common in high grade and type II endometrial cancer.8
284237372017RMP promotes epithelial-mesenchymal transition through NF-κB/CSN2/Snail pathway in hepatocellular carcinoma.9
271054892016Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1.9
275056732016Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms.48
277808692016URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.14
271054892016Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1.9
275056732016Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms.48
277808692016URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.14
255271752015Characterization of the 19q12 amplification including CCNE1 and URI in different epithelial ovarian cancer subtypes.15

Citation

Dessen P

URI1 (URI1 prefoldin like chaperone)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52232/uri1-(uri1-prefoldin-like-chaperone)