Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3658
MIM: 147582
HGNC: 6115
Ensembl: ENSG00000136381
Variants:
dbSNP: 3658
ClinVar: 3658
TCGA: ENSG00000136381
COSMIC: IREB2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36600258 | 2023 | KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2. | 2 |
| 36600258 | 2023 | KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2. | 2 |
| 35599631 | 2022 | MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2. | 20 |
| 35599631 | 2022 | MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2. | 20 |
| 31907996 | 2020 | Mdm2 is a target and mediator of IRP2 in cell growth control. | 9 |
| 32126207 | 2020 | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. | 49 |
| 32276991 | 2020 | Iron Regulatory Protein 2 Exerts its Oncogenic Activities by Suppressing TAp63 Expression. | 6 |
| 32813008 | 2020 | IRP2-Hif1α/Hif2α signaling: a novel mechanism of metabolic switch from aerobic glycolysis to oxidative phosphorylation. | 0 |
| 31907996 | 2020 | Mdm2 is a target and mediator of IRP2 in cell growth control. | 9 |
| 32126207 | 2020 | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. | 49 |
| 32276991 | 2020 | Iron Regulatory Protein 2 Exerts its Oncogenic Activities by Suppressing TAp63 Expression. | 6 |
| 32813008 | 2020 | IRP2-Hif1α/Hif2α signaling: a novel mechanism of metabolic switch from aerobic glycolysis to oxidative phosphorylation. | 0 |
| 31092704 | 2019 | Zinc induces iron uptake and DMT1 expression in Caco-2 cells via a PI3K/IRP2 dependent mechanism. | 8 |
| 31332290 | 2019 | Iron regulatory protein 2 is a suppressor of mutant p53 in tumorigenesis. | 8 |
| 31092704 | 2019 | Zinc induces iron uptake and DMT1 expression in Caco-2 cells via a PI3K/IRP2 dependent mechanism. | 8 |
Citation
Dessen P
IREB2 (iron responsive element binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-06-01
Online version: http://atlasgeneticsoncology.org/gene/52239/ireb2-(iron-responsive-element-binding-protein-2)
