AKTIP (AKT interacting protein)

2011-06-01  

Identity

HGNC
LOCATION
16q12.2
LOCUSID
ALIAS
FT1,FTS

Other Information

Locus ID:

NCBI: 64400
MIM: 608483
HGNC: 16710
Ensembl: ENSG00000166971

Variants:

dbSNP: 64400
ClinVar: 64400
TCGA: ENSG00000166971
COSMIC: AKTIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166971ENST00000300245Q9H8T0
ENSG00000166971ENST00000300245A0A024R6S6
ENSG00000166971ENST00000394657Q9H8T0
ENSG00000166971ENST00000394657A0A024R6T5
ENSG00000166971ENST00000563928H3BRV2
ENSG00000166971ENST00000564497H3BRT7
ENSG00000166971ENST00000565408H3BVH0
ENSG00000166971ENST00000568022H3BM79
ENSG00000166971ENST00000568596H3BNB8
ENSG00000166971ENST00000570004Q9H8T0
ENSG00000166971ENST00000570004A0A024R6T5
ENSG00000166971ENST00000570041H3BSX7

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187996222008An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.43
147493672004Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt.32
206353892011Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer.25
261105282015AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance.16
192700262009Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.11
275121402016The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.9
249719342014EGF-induced expression of Fused Toes Homolog (FTS) facilitates epithelial-mesenchymal transition and promotes cell migration in ME180 cervical cancer cells.6
201323172010Association between AKT1 but not AKTIP genetic variants and increased risk for suicidal behavior in bipolar patients.5
209453722011FTS (fused toes homolog) a novel oncoprotein involved in uterine cervical carcinogenesis and a potential diagnostic marker for cervical cancer.4
240228752014Genetic variant of AKT1 and AKTIP associated with late-onset depression in a Brazilian population.4

Citation

Dessen P

AKTIP (AKT interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52260/aktip-(akt-interacting-protein)