Identity
HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
OATP-B,OATP2B1,OATPB,SLC21A9
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11309
MIM: 604988
HGNC: 10962
Ensembl: ENSG00000137491
Variants:
dbSNP: 11309
ClinVar: 11309
TCGA: ENSG00000137491
COSMIC: SLCO2B1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA133950441 | hmg coa reductase inhibitors | Chemical | Pathway | associated | |||
| PA134308647 | rosuvastatin | Chemical | Pathway | associated | |||
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PK | PD | 19151602, 23970434 |
| PA448500 | atorvastatin | Chemical | Pathway | associated | |||
| PA449621 | fexofenadine | Chemical | ClinicalAnnotation | associated | PK | 21280267 | |
| PA449688 | fluvastatin | Chemical | Pathway | associated | |||
| PA450272 | lovastatin | Chemical | Pathway | associated | |||
| PA450546 | montelukast | Chemical | ClinicalAnnotation | associated | PK | PD | 19151602, 23970434 |
| PA450573 | nadolol | Chemical | Literature, MultilinkAnnotation | not associated | 24419562 | ||
| PA451089 | pravastatin | Chemical | Pathway | associated | |||
| PA451363 | simvastatin | Chemical | Literature, MultilinkAnnotation, Pathway | associated | 24598718 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37856781 | 2024 | SLCO1B3 and SLCO2B1 genotypes, androgen deprivation therapy, and prostate cancer outcomes: a prospective cohort study and meta-analysis. | 0 |
| 38423481 | 2024 | Roles of breast cancer resistance protein and organic anion transporting polypeptide 2B1 in gastrointestinal toxicity induced by SN-38 under inflammatory conditions. | 0 |
| 38432624 | 2024 | The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B1. | 0 |
| 37856781 | 2024 | SLCO1B3 and SLCO2B1 genotypes, androgen deprivation therapy, and prostate cancer outcomes: a prospective cohort study and meta-analysis. | 0 |
| 38423481 | 2024 | Roles of breast cancer resistance protein and organic anion transporting polypeptide 2B1 in gastrointestinal toxicity induced by SN-38 under inflammatory conditions. | 0 |
| 38432624 | 2024 | The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B1. | 0 |
| 36253893 | 2023 | Genetic Polymorphisms in SLCO2B1 and ABCC1 Conjointly Modulate Atorvastatin Intracellular Accumulation in HEK293 Recombinant Cell Lines. | 0 |
| 36253893 | 2023 | Genetic Polymorphisms in SLCO2B1 and ABCC1 Conjointly Modulate Atorvastatin Intracellular Accumulation in HEK293 Recombinant Cell Lines. | 0 |
| 34762930 | 2022 | Association of genetic polymorphisms with local steroid metabolism in human benign breasts. | 2 |
| 34762930 | 2022 | Association of genetic polymorphisms with local steroid metabolism in human benign breasts. | 2 |
| 33723795 | 2021 | Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo. | 6 |
| 34628357 | 2021 | Differences in transport function of the human and rat orthologue of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1). | 3 |
| 33723795 | 2021 | Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo. | 6 |
| 34628357 | 2021 | Differences in transport function of the human and rat orthologue of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1). | 3 |
| 31849283 | 2020 | Germline variants and response to systemic therapy in advanced prostate cancer. | 1 |
Citation
Dessen P
SLCO2B1 (solute carrier organic anion transporter family member 2B1)
Atlas Genet Cytogenet Oncol Haematol. 2011-07-01
Online version: http://atlasgeneticsoncology.org/gene/52268/slco2b1-(solute-carrier-organic-anion-transporter-family-member-2b1)
