MYO1C (myosin IC)

2011-07-01  

Identity

HGNC
MYO1C
LOCATION
17p13.3
LOCUSID
4641
ALIAS
MMI-beta,MMIb,NMI,myr2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4641
MIM: 606538
HGNC: 7597
Ensembl: ENSG00000197879

Variants:

dbSNP: 4641
ClinVar: 4641
TCGA: ENSG00000197879
COSMIC: MYO1C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197879ENST00000361007O00159
ENSG00000197879ENST00000545534F5H6E2
ENSG00000197879ENST00000570490I3L501
ENSG00000197879ENST00000570984O00159
ENSG00000197879ENST00000573853I3L3Y6
ENSG00000197879ENST00000575011I3L2C3
ENSG00000197879ENST00000575158O00159
ENSG00000197879ENST00000575335I3L3F5
ENSG00000197879ENST00000646049O00159
ENSG00000197879ENST00000648446O00159
ENSG00000197879ENST00000648651O00159

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Fcgamma receptor (FCGR) dependent phagocytosisREACTOMER-HSA-2029480
Regulation of actin dynamics for phagocytic cup formationREACTOMER-HSA-2029482
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148
Positive epigenetic regulation of rRNA expressionREACTOMER-HSA-5250913
B-WICH complex positively regulates rRNA expressionREACTOMER-HSA-5250924

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379534662024RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C.1
379534662024RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C.1
367369502023Elevation of truncated (48 kDa) form of unconventional myosin 1C in blood serum correlates with severe Covid-19.0
367818392023m(6)A-modified circRNA MYO1C participates in the tumor immune surveillance of pancreatic ductal adenocarcinoma through m(6)A/PD-L1 manner.8
367369502023Elevation of truncated (48 kDa) form of unconventional myosin 1C in blood serum correlates with severe Covid-19.0
367818392023m(6)A-modified circRNA MYO1C participates in the tumor immune surveillance of pancreatic ductal adenocarcinoma through m(6)A/PD-L1 manner.8
332015342021Isolation and identification in human blood serum of the proteins possessing the ability to bind with 48 kDa form of unconventional myosin 1c and their possible diagnostic and prognostic value.2
340195932021Myosin 1C isoform A is a novel candidate diagnostic marker for prostate cancer.5
343804382021SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line.2
332015342021Isolation and identification in human blood serum of the proteins possessing the ability to bind with 48 kDa form of unconventional myosin 1c and their possible diagnostic and prognostic value.2
340195932021Myosin 1C isoform A is a novel candidate diagnostic marker for prostate cancer.5
343804382021SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line.2
308724582019MYO1C stabilizes actin and facilitates the arrival of transport carriers at the Golgi complex.15
308724582019MYO1C stabilizes actin and facilitates the arrival of transport carriers at the Golgi complex.15
291790372018Nuclear myosin 1 associates with papillomavirus E2 regulatory protein and influences viral replication.2

Citation

Dessen P

MYO1C (myosin IC)

Atlas Genet Cytogenet Oncol Haematol. 2011-07-01

Online version: http://atlasgeneticsoncology.org/gene/52278/myo1c-(myosin-ic)