Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 91012
MIM: 615335
HGNC: 23749
Ensembl: ENSG00000139624
Variants:
dbSNP: 91012
ClinVar: 91012
TCGA: ENSG00000139624
COSMIC: CERS5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38244710 | 2024 | Identification of CERS5 as a molecular biomarker in pan-cancer through multiple omics integrative analysis. | 1 |
| 38244710 | 2024 | Identification of CERS5 as a molecular biomarker in pan-cancer through multiple omics integrative analysis. | 1 |
| 30059758 | 2018 | Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy. | 18 |
| 30059758 | 2018 | Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy. | 18 |
| 28424433 | 2017 | [Investigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells]. | 0 |
| 28424433 | 2017 | [Investigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells]. | 0 |
| 26887952 | 2016 | Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. | 28 |
| 27280497 | 2016 | LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 Activity. | 4 |
| 26887952 | 2016 | Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. | 28 |
| 27280497 | 2016 | LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 Activity. | 4 |
| 25779024 | 2015 | Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers. | 10 |
| 25779024 | 2015 | Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers. | 10 |
| 20406683 | 2010 | Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. | 111 |
| 20406683 | 2010 | Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. | 111 |
| 18676372 | 2008 | Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. | 40 |
Citation
Dessen P
CERS5 (ceramide synthase 5)
Atlas Genet Cytogenet Oncol Haematol. 2011-07-01
Online version: http://atlasgeneticsoncology.org/gene/52286/cers5-(ceramide-synthase-5)
