LXN (latexin)

2011-08-01  

Identity

HGNC
LXN
LOCATION
3q25.32
LOCUSID
56925
ALIAS
ECI,TCI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56925
MIM: 609305
HGNC: 13347
Ensembl: ENSG00000079257

Variants:

dbSNP: 56925
ClinVar: 56925
TCGA: ENSG00000079257
COSMIC: LXN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000079257ENST00000264265Q9BS40
ENSG00000079257ENST00000482640H7C5A4

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369495002023Circ_0002715 promotes the development of osteoarthritis through regulating LXN by sponging miR-127-5p.1
369495002023Circ_0002715 promotes the development of osteoarthritis through regulating LXN by sponging miR-127-5p.1
309146562019The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy.9
309146562019The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy.9
296084882018Latexin and hematopoiesis.3
296084882018Latexin and hematopoiesis.3
280877402017Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance.7
280877402017Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance.7
265305302016Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma.5
265305302016Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma.5
243992462014Latexin exhibits tumor suppressor potential in hepatocellular carcinoma.14
255514722014Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells.5
243992462014Latexin exhibits tumor suppressor potential in hepatocellular carcinoma.14
255514722014Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells.5
233644792013The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.20

Citation

Dessen P

LXN (latexin)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52304/lxn-(latexin)