SNTA1 (syntrophin alpha 1)

2011-08-01 Affiliation

Identity

HGNC

SNTA1

LOCATION

20q11.21

LOCUSID

6640

ALIAS

LQT12,SNT1,TACIP1,dJ1187J4.5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 6640
MIM: 601017
HGNC: 11167
Ensembl: ENSG00000101400

Variants:

dbSNP: 6640
ClinVar: 6640
TCGA: ENSG00000101400
COSMIC: SNTA1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000101400	ENST00000217381	Q13424

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35762211	2022	SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients.	8
35762211	2022	SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients.	8
33515365	2021	Jasplakinolide Attenuates Cell Migration by Impeding Alpha-1-syntrophin Protein Phosphorylation in Breast Cancer Cells.	7
33834492	2021	α-Syntrophin alleviates ER stress to maintain protein homeostasis during myoblast differentiation.	1
33515365	2021	Jasplakinolide Attenuates Cell Migration by Impeding Alpha-1-syntrophin Protein Phosphorylation in Breast Cancer Cells.	7
33834492	2021	α-Syntrophin alleviates ER stress to maintain protein homeostasis during myoblast differentiation.	1
31881201	2020	Alpha-syntrophin deficiency protects against non-alcoholic steatohepatitis associated increase of macrophages, CD8(+) T-cells and galectin-3 in the liver.	0
31881201	2020	Alpha-syntrophin deficiency protects against non-alcoholic steatohepatitis associated increase of macrophages, CD8(+) T-cells and galectin-3 in the liver.	0
30033487	2018	Alpha-syntrophin dependent expression of tubulin alpha 8 protein in hepatocytes.	1
30033487	2018	Alpha-syntrophin dependent expression of tubulin alpha 8 protein in hepatocytes.	1
28520217	2017	The gene encoding the inwardly rectifying potassium channel Kir4.1 may be involved in sudden infant death syndrome.	5
28941732	2017	The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma.	0
28520217	2017	The gene encoding the inwardly rectifying potassium channel Kir4.1 may be involved in sudden infant death syndrome.	5
28941732	2017	The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma.	0
27028743	2016	α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.	6

Citation

Dessen P

SNTA1 (syntrophin alpha 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52306/js/lib/favicon/hgnc