CANT1 (calcium activated nucleotidase 1)

2011-08-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
DBQD,DBQD1,EDM7,SCAN-1,SCAN1,SHAPY
FUSION GENES

Other Information

Locus ID:

NCBI: 124583
MIM: 613165
HGNC: 19721
Ensembl: ENSG00000171302

Variants:

dbSNP: 124583
ClinVar: 124583
TCGA: ENSG00000171302
COSMIC: CANT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171302ENST00000302345Q8WVQ1
ENSG00000171302ENST00000302345A0A024R8U8
ENSG00000171302ENST00000392446Q8WVQ1
ENSG00000171302ENST00000392446A0A024R8U8
ENSG00000171302ENST00000586916K7EQT4
ENSG00000171302ENST00000588075K7EKT2
ENSG00000171302ENST00000588611K7EKW6
ENSG00000171302ENST00000590370K7EMT2
ENSG00000171302ENST00000591625K7EQD4
ENSG00000171302ENST00000591773Q8WVQ1
ENSG00000171302ENST00000591773A0A024R8U8
ENSG00000171302ENST00000591811K7EIP9
ENSG00000171302ENST00000592033K7EIP9
ENSG00000171302ENST00000592228K7EN15
ENSG00000171302ENST00000620915Q8WVQ1
ENSG00000171302ENST00000620915A0A024R8U8

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383692652024Pan-cancer analysis predicts CANT1 as a potential prognostic, immunologic biomarker.1
383692652024Pan-cancer analysis predicts CANT1 as a potential prognostic, immunologic biomarker.1
378580612023Upregulated CANT1 is correlated with poor prognosis in hepatocellular carcinoma.0
378580612023Upregulated CANT1 is correlated with poor prognosis in hepatocellular carcinoma.0
350683362022Calcium-activated nucleotides 1 (CANT1)-driven nuclear factor-k-gene binding (NF-ĸB) signaling pathway facilitates the lung cancer progression.6
350683362022Calcium-activated nucleotides 1 (CANT1)-driven nuclear factor-k-gene binding (NF-ĸB) signaling pathway facilitates the lung cancer progression.6
319880672020Pseudodiastrophic dysplasia expands the known phenotypic spectrum of defects in proteoglycan biosynthesis.7
329076082020Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: the disappearance of dimerization may indicate the change of protein conformation and even function.2
319880672020Pseudodiastrophic dysplasia expands the known phenotypic spectrum of defects in proteoglycan biosynthesis.7
329076082020Cloning, expression and enzyme activity delineation of two novel CANT1 mutations: the disappearance of dimerization may indicate the change of protein conformation and even function.2
311023002019Calcium-activated nucleotidase 1 silencing inhibits proliferation, migration, and invasion in human clear cell renal cell carcinoma.8
311023002019Calcium-activated nucleotidase 1 silencing inhibits proliferation, migration, and invasion in human clear cell renal cell carcinoma.8
283306942017CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma.27
287422822017MED resulting from recessively inherited mutations in the gene encoding calcium-activated nucleotidase CANT1.10
283306942017CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma.27

Citation

Dessen P

CANT1 (calcium activated nucleotidase 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52312/cant1-(calcium-activated-nucleotidase-1)