CABYR (calcium binding tyrosine phosphorylation regulated)

2011-08-01  

Identity

HGNC
LOCATION
18q11.2
LOCUSID
ALIAS
CABYRa,CABYRc,CABYRc/d,CABYRe,CBP86,CT88,FSP-2,FSP2
FUSION GENES

Other Information

Locus ID:

NCBI: 26256
MIM: 612135
HGNC: 15569
Ensembl: ENSG00000154040

Variants:

dbSNP: 26256
ClinVar: 26256
TCGA: ENSG00000154040
COSMIC: CABYR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154040ENST00000327201O75952
ENSG00000154040ENST00000399481O75952
ENSG00000154040ENST00000399496O75952
ENSG00000154040ENST00000399499O75952
ENSG00000154040ENST00000415309O75952
ENSG00000154040ENST00000463087O75952
ENSG00000154040ENST00000463087A0A024RC21
ENSG00000154040ENST00000486759O75952
ENSG00000154040ENST00000486759A0A024RC21
ENSG00000154040ENST00000577705J3QQK7
ENSG00000154040ENST00000579102J3KT09
ENSG00000154040ENST00000579956J3KRI0
ENSG00000154040ENST00000581397G9BQT7
ENSG00000154040ENST00000581872J3KRI0
ENSG00000154040ENST00000582229J3KTE8
ENSG00000154040ENST00000584752J3KRI0
ENSG00000154040ENST00000585037J3QLW5
ENSG00000154040ENST00000621648O75952
ENSG00000154040ENST00000621648A0A024RC21
ENSG00000154040ENST00000627314A0A0D9SFQ2

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
118208182002CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation.45
157527682005Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain.10
243622512014Knockdown of CABYR-a/b increases chemosensitivity of human non-small cell lung cancer cells through inactivation of Akt.10
212402912011CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.9
281216272017Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells.9
268436202016Depletion of CABYR-a/b sensitizes lung cancer cells to TRAIL-induced apoptosis through YAP/p73-mediated DR5 upregulation.5
161392642005Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A.4
222854302012The expression and effects the CABYR-c transcript of CABYR gene in hepatocellular carcinoma.3
212745092011Expression of the sperm fibrous sheath protein CABYR in human cancers and identification of α-enolase as an interacting partner of CABYR-a.2

Citation

Dessen P

CABYR (calcium binding tyrosine phosphorylation regulated)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52313/cabyr-(calcium-binding-tyrosine-phosphorylation-regulated)