Identity
HGNC
LOCATION
20q11.21
LOCUSID
ALIAS
LUNX,NASG,PLUNC,SPLUNC1,SPURT,bA49G10.5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51297
MIM: 607412
HGNC: 15749
Ensembl: ENSG00000198183
Variants:
dbSNP: 51297
ClinVar: 51297
TCGA: ENSG00000198183
COSMIC: BPIFA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198183 | ENST00000354297 | Q9NP55 |
| ENSG00000198183 | ENST00000375413 | Q9NP55 |
| ENSG00000198183 | ENST00000375422 | Q9NP55 |
| ENSG00000198183 | ENST00000618484 | Q9NP55 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Antimicrobial peptides | REACTOME | R-HSA-6803157 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36709941 | 2023 | [Correlation between the mRNA levels of BCRP and LUNX genes and pathological types and stages of patients with non-small cell lung cancer]. | 0 |
| 37223955 | 2023 | Lung SPLUNC1 Peptide Derivatives in the Lipid Membrane Headgroup Kill Gram-Negative Planktonic and Biofilm Bacteria. | 1 |
| 38053993 | 2023 | CC16 drives VLA-2-dependent SPLUNC1 expression. | 0 |
| 36709941 | 2023 | [Correlation between the mRNA levels of BCRP and LUNX genes and pathological types and stages of patients with non-small cell lung cancer]. | 0 |
| 37223955 | 2023 | Lung SPLUNC1 Peptide Derivatives in the Lipid Membrane Headgroup Kill Gram-Negative Planktonic and Biofilm Bacteria. | 1 |
| 38053993 | 2023 | CC16 drives VLA-2-dependent SPLUNC1 expression. | 0 |
| 35581745 | 2022 | SPLUNC1 is a negative regulator of the Orai1 Ca(2+) channel. | 1 |
| 36175598 | 2022 | SPLUNC1 regulates LPS-induced progression of nasopharyngeal carcinoma and proliferation of myeloid-derived suppressor cells. | 0 |
| 36519134 | 2022 | BPIFA1 is a secreted biomarker of differentiating human airway epithelium. | 1 |
| 35581745 | 2022 | SPLUNC1 is a negative regulator of the Orai1 Ca(2+) channel. | 1 |
| 36175598 | 2022 | SPLUNC1 regulates LPS-induced progression of nasopharyngeal carcinoma and proliferation of myeloid-derived suppressor cells. | 0 |
| 36519134 | 2022 | BPIFA1 is a secreted biomarker of differentiating human airway epithelium. | 1 |
| 31504285 | 2020 | A Rare Mutation in SPLUNC1 Affects Bacterial Adherence and Invasion in Meningococcal Disease. | 4 |
| 31931521 | 2020 | Immunomodulatory function of the cystic fibrosis modifier gene BPIFA1. | 8 |
| 32680508 | 2020 | The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia. | 3 |
Citation
Dessen P
BPIFA1 (BPI fold containing family A member 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-08-01
Online version: http://atlasgeneticsoncology.org/gene/52329/bpifa1-(bpi-fold-containing-family-a-member-1)
