Identity
HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
HBO1,HBOA,MYST2,ZC2HC7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11143
MIM: 609880
HGNC: 17016
Ensembl: ENSG00000136504
Variants:
dbSNP: 11143
ClinVar: 11143
TCGA: ENSG00000136504
COSMIC: KAT7
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HATs acetylate histones | REACTOME | R-HSA-3214847 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37779410 | 2024 | Adipose Mesenchymal Stem Cell-derived Exosomes Enhanced Glycolysis through the SIX1/HBO1 Pathway against Oxygen and Glucose Deprivation Injury in Human Umbilical Vein Endothelial Cells. | 1 |
| 38421638 | 2024 | HBO1 determines SMAD action in pluripotency and mesendoderm specification. | 0 |
| 38797155 | 2024 | KAT7 serves as an oncogenic gene and regulates CCL3 expression via STAT1 signaling in osteosarcoma. | 0 |
| 37779410 | 2024 | Adipose Mesenchymal Stem Cell-derived Exosomes Enhanced Glycolysis through the SIX1/HBO1 Pathway against Oxygen and Glucose Deprivation Injury in Human Umbilical Vein Endothelial Cells. | 1 |
| 38421638 | 2024 | HBO1 determines SMAD action in pluripotency and mesendoderm specification. | 0 |
| 38797155 | 2024 | KAT7 serves as an oncogenic gene and regulates CCL3 expression via STAT1 signaling in osteosarcoma. | 0 |
| 36724120 | 2023 | KAT7 promotes radioresistance through upregulating PI3K/AKT signaling in breast cancer. | 2 |
| 37258203 | 2023 | The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy. | 2 |
| 37542030 | 2023 | Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia. | 2 |
| 36724120 | 2023 | KAT7 promotes radioresistance through upregulating PI3K/AKT signaling in breast cancer. | 2 |
| 37258203 | 2023 | The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy. | 2 |
| 37542030 | 2023 | Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia. | 2 |
| 35266843 | 2022 | KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity. | 2 |
| 35637972 | 2022 | HBO1 induces histone acetylation and is important for non-small cell lung cancer cell growth. | 7 |
| 35868058 | 2022 | KAT7 promoted gastric cancer progression through promoting YAP1 activation. | 1 |
Citation
Dessen P
KAT7 (lysine acetyltransferase 7)
Atlas Genet Cytogenet Oncol Haematol. 2011-08-01
Online version: http://atlasgeneticsoncology.org/gene/52346/kat7-(lysine-acetyltransferase-7)
