KLF3 (Kruppel like factor 3)

2011-09-01  

Identity

HGNC
LOCATION
4p14
LOCUSID
ALIAS
BKLF
FUSION GENES

Other Information

Locus ID:

NCBI: 51274
MIM: 609392
HGNC: 16516
Ensembl: ENSG00000109787

Variants:

dbSNP: 51274
ClinVar: 51274
TCGA: ENSG00000109787
COSMIC: KLF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109787ENST00000261438P57682
ENSG00000109787ENST00000261438A0A024R9T8
ENSG00000109787ENST00000514033P57682

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380734412024Molecular Expression and Prognostic Implications of Krüppel-Like Factor 3 (KLF3) in Clear Cell Renal Cell Carcinoma.1
380734412024Molecular Expression and Prognostic Implications of Krüppel-Like Factor 3 (KLF3) in Clear Cell Renal Cell Carcinoma.1
368278692023KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway.3
375972422023microRNA-92b-3p augments colon cancer development through inhibiting KLF3.0
376007832023Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.0
379450212023Decreased KLF3 Expression via miR-660-5p Targeting Suppresses Gastric Cancer Cell Progression.0
368278692023KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway.3
375972422023microRNA-92b-3p augments colon cancer development through inhibiting KLF3.0
376007832023Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.0
379450212023Decreased KLF3 Expression via miR-660-5p Targeting Suppresses Gastric Cancer Cell Progression.0
337284882022microRNA-21-5p from M2 macrophage-derived extracellular vesicles promotes the differentiation and activity of pancreatic cancer stem cells by mediating KLF3.34
344075482022Hepatic Meteorin-like and Krüppel-like Factor 3 are Associated with Weight Loss and Liver Injury.4
349370392022Exosome miR-23a-3p from Osteoblast Alleviates Spinal Cord Ischemia/Reperfusion Injury by Down-Regulating KLF3-Activated CCNL2 Transcription.1
353116202022Fat mass and obesity associated (FTO)-mediated N6-methyladenosine modification of Krüppel-like factor 3 (KLF3) promotes osteosarcoma progression.11
355498152022Bone mesenchymal stem cells (BMSCs)-derived exosomal microRNA-21-5p regulates Kruppel-like factor 3 (KLF3) to promote osteoblast proliferation in vitro.9

Citation

Dessen P

KLF3 (Kruppel like factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-09-01

Online version: http://atlasgeneticsoncology.org/gene/52364/