SMOC1 (SPARC related modular calcium binding 1)

2011-09-01  

Identity

HGNC
LOCATION
14q24.2
LOCUSID
ALIAS
OAS
FUSION GENES

Other Information

Locus ID:

NCBI: 64093
MIM: 608488
HGNC: 20318
Ensembl: ENSG00000198732

Variants:

dbSNP: 64093
ClinVar: 64093
TCGA: ENSG00000198732
COSMIC: SMOC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198732ENST00000361956Q9H4F8
ENSG00000198732ENST00000381280Q9H4F8
ENSG00000198732ENST00000381280A0A024R6E0

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384296552024Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas.0
384296552024Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas.0
337571262022SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling.5
337571262022SPARC-related modular calcium binding 1 regulates aortic valve calcification by disrupting BMPR-II/p-p38 signalling.5
334847012021SMOC1 and IL-4 and IL-13 Cytokines Interfere with Ca(2+) Mobilization in Primary Human Keratinocytes.2
335293322021Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes.10
334847012021SMOC1 and IL-4 and IL-13 Cytokines Interfere with Ca(2+) Mobilization in Primary Human Keratinocytes.2
335293322021Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes.10
304451502019A fetal case of microphthalmia and limb anomalies with abnormal neuronal migration associated with SMOC1 biallelic variants.2
304451502019A fetal case of microphthalmia and limb anomalies with abnormal neuronal migration associated with SMOC1 biallelic variants.2
280855232017A novel homozygous variant in the SMOC1 gene underlying Waardenburg anophthalmia syndrome.3
288078692017A novel mutation in SMOC1 and variable phenotypic expression in two patients with Waardenburg anophthalmia syndrome.5
280855232017A novel homozygous variant in the SMOC1 gene underlying Waardenburg anophthalmia syndrome.3
288078692017A novel mutation in SMOC1 and variable phenotypic expression in two patients with Waardenburg anophthalmia syndrome.5
271013912016SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.0

Citation

Dessen P

SMOC1 (SPARC related modular calcium binding 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-09-01

Online version: http://atlasgeneticsoncology.org/gene/52374/smoc1-(sparc-related-modular-calcium-binding-1)