Identity
HGNC
LOCATION
19q13.41
LOCUSID
ALIAS
S2V,SIGLECL1,SLG,Siglec-XII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 89858
MIM: 606094
HGNC: 15482
Ensembl: ENSG00000254521
Variants:
dbSNP: 89858
ClinVar: 89858
TCGA: ENSG00000254521
COSMIC: SIGLEC12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000254521 | ENST00000291707 | Q96PQ1 |
| ENSG00000254521 | ENST00000596742 | M0QYF3 |
| ENSG00000254521 | ENST00000598614 | Q96PQ1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 23690342 | 2013 | Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. | 21 |
| 23690342 | 2013 | Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. | 21 |
| 21555517 | 2011 | SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. | 32 |
| 21555517 | 2011 | SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. | 32 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
SIGLEC12 (sialic acid binding Ig like lectin 12)
Atlas Genet Cytogenet Oncol Haematol. 2011-09-01
Online version: http://atlasgeneticsoncology.org/gene/52383/siglec12-(sialic-acid-binding-ig-like-lectin-12)
