OLR1 (oxidized low density lipoprotein receptor 1)

2011-10-01  

Identity

HGNC
OLR1
LOCATION
12p13.2
LOCUSID
4973
ALIAS
CLEC8A,LOX1,LOXIN,SCARE1,SLOX1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4973
MIM: 602601
HGNC: 8133
Ensembl: ENSG00000173391

Variants:

dbSNP: 4973
ClinVar: 4973
TCGA: ENSG00000173391
COSMIC: OLR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173391ENST00000309539P78380
ENSG00000173391ENST00000309539A0A024RAU0
ENSG00000173391ENST00000339968J3QTI8
ENSG00000173391ENST00000432556P78380
ENSG00000173391ENST00000538745F5H3G7
ENSG00000173391ENST00000538873F5H0N6
ENSG00000173391ENST00000539518F5H7N8
ENSG00000173391ENST00000543414F5H001
ENSG00000173391ENST00000543993B7ZAN8
ENSG00000173391ENST00000544577F5GZH1
ENSG00000173391ENST00000545927P78380

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
PPAR signaling pathwayKEGGhsa03320
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
376686842024Associations of CKIP-1 and LOX-1 polymorphisms with the risk of type 2 diabetes mellitus with hypertension among Chinese adults.0
385012472024LOX-1 and MMP-9 Inhibition Attenuates the Detrimental Effects of Delayed rt-PA Therapy and Improves Outcomes After Acute Ischemic Stroke.2
388215882024Elucidating the Role of Let-7d-5p and OLR1 in the Progression and Prognosis of Oral Squamous Cell Carcinoma via FAK/P53 Signaling Axis.0
376686842024Associations of CKIP-1 and LOX-1 polymorphisms with the risk of type 2 diabetes mellitus with hypertension among Chinese adults.0
385012472024LOX-1 and MMP-9 Inhibition Attenuates the Detrimental Effects of Delayed rt-PA Therapy and Improves Outcomes After Acute Ischemic Stroke.2
388215882024Elucidating the Role of Let-7d-5p and OLR1 in the Progression and Prognosis of Oral Squamous Cell Carcinoma via FAK/P53 Signaling Axis.0
362640492023Up-regulation of oxidized low-density lipoprotein receptor 1 correlates with decreased miR-106b-5p, miR-93-5p, miR-3129-5p, miR-199b-3p, and miR-4465, higher recurrence rate, and poor prognosis in ovarian cancer.0
366473172023Genetic variations in OLR1 gene associated with PCOS and atherosclerotic risk factors.1
370894482023Expression of OLR1 gene on tumor-associated macrophages of head and neck squamous cell carcinoma, and its correlation with clinical outcome.4
372712502023TM6SF2 reduces lipid accumulation in vascular smooth muscle cells by inhibiting LOX-1 and CD36 expression.0
374212872023Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm.0
362640492023Up-regulation of oxidized low-density lipoprotein receptor 1 correlates with decreased miR-106b-5p, miR-93-5p, miR-3129-5p, miR-199b-3p, and miR-4465, higher recurrence rate, and poor prognosis in ovarian cancer.0
366473172023Genetic variations in OLR1 gene associated with PCOS and atherosclerotic risk factors.1
370894482023Expression of OLR1 gene on tumor-associated macrophages of head and neck squamous cell carcinoma, and its correlation with clinical outcome.4
372712502023TM6SF2 reduces lipid accumulation in vascular smooth muscle cells by inhibiting LOX-1 and CD36 expression.0

Citation

Dessen P

OLR1 (oxidized low density lipoprotein receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52401/olr1-(oxidized-low-density-lipoprotein-receptor-1)