CGGBP1 (CGG triplet repeat binding protein 1)

2011-10-01  

Identity

HGNC
CGGBP1
LOCATION
3p11.1
LOCUSID
8545
ALIAS
CGGBP,p20-CGGBP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8545
MIM: 603363
HGNC: 1888
Ensembl: ENSG00000163320

Variants:

dbSNP: 8545
ClinVar: 8545
TCGA: ENSG00000163320
COSMIC: CGGBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163320ENST00000309534Q9UFW8
ENSG00000163320ENST00000398392Q9UFW8
ENSG00000163320ENST00000462901Q9UFW8
ENSG00000163320ENST00000467332C9JUJ0
ENSG00000163320ENST00000482016Q9UFW8

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
217331962011CGGBP1 regulates cell cycle in cancer cells.14
146678142004Gene structure and expression of the 5'-(CGG)(n)-3'-binding protein (CGGBP1).12
241964422014CGGBP1 phosphorylation constitutes a telomere-protection signal.7
254830502016Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs.6
259815272015CGGBP1 mitigates cytosine methylation at repetitive DNA sequences.5
244910492014[Over-expressed microRNA-7 inhibits the growth of human lung cancer cells via suppressing CGGBP1 expression].3
201410362009[The role of ZF5 and CGGBP-20 transcription factors in expression regulation of human FMR1 gene responsible for X-fragile syndrome].2
263066472016Defining the role of the CGGBP1 protein in FMR1 gene expression.2
264826562015CGGBP1--an indispensable protein with ubiquitous cytoprotective functions.2
197285372008Fragile X gene stability in Basque Valleys: prevalence of premutation and intermediate alleles.1

Citation

Dessen P

CGGBP1 (CGG triplet repeat binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52418/cggbp1-(cgg-triplet-repeat-binding-protein-1)