TRIM31 (tripartite motif containing 31)

2011-10-01  

Identity

HGNC
LOCATION
6p22.1
LOCUSID
ALIAS
C6orf13,HCG1,HCGI,RNF

Other Information

Locus ID:

NCBI: 11074
MIM: 609316
HGNC: 16289
Ensembl: ENSG00000204616

Variants:

dbSNP: 11074
ClinVar: 11074
TCGA: ENSG00000204616
COSMIC: TRIM31

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204616ENST00000376734Q9BZY9
ENSG00000204616ENST00000376734Q2L6J1

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
354291732023Tripartite motif-containing protein 31 confers protection against nonalcoholic steatohepatitis by deactivating mitogen-activated protein kinase kinase kinase 7.9
374980682023TRIM31 promotes the progression of oral squamous cell carcinoma through upregulating AKT phosphorylation and subsequent cellular glycolysis.0
354291732023Tripartite motif-containing protein 31 confers protection against nonalcoholic steatohepatitis by deactivating mitogen-activated protein kinase kinase kinase 7.9
374980682023TRIM31 promotes the progression of oral squamous cell carcinoma through upregulating AKT phosphorylation and subsequent cellular glycolysis.0
359413262022Exosomal microRNA-551b-3p from bone marrow-derived mesenchymal stromal cells inhibits breast cancer progression via regulating TRIM31/Akt signaling.4
359708572022Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers.8
360945012022CircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis.5
359413262022Exosomal microRNA-551b-3p from bone marrow-derived mesenchymal stromal cells inhibits breast cancer progression via regulating TRIM31/Akt signaling.4
359708572022Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers.8
360945012022CircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis.5
341054762021[Effect of TRIM31 Gene Silencing on the Proliferation and Apoptosis of U266 Cells and Its Mechanism].0
346500492021Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.25
341054762021[Effect of TRIM31 Gene Silencing on the Proliferation and Apoptosis of U266 Cells and Its Mechanism].0
346500492021Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.25
320202062020MicroRNA‑29c‑3p acts as a tumor suppressor gene and inhibits tumor progression in hepatocellular carcinoma by targeting TRIM31.11

Citation

Dessen P

TRIM31 (tripartite motif containing 31)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52447/