Identity
HGNC
LOCATION
6p21.31
LOCUSID
ALIAS
CEGF3,SSFSC2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 222663
MIM: 614708
HGNC: 13655
Ensembl: ENSG00000146197
Variants:
dbSNP: 222663
ClinVar: 222663
TCGA: ENSG00000146197
COSMIC: SCUBE3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000146197 | ENST00000274938 | Q8IX30 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37189178 | 2023 | Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration. | 2 |
| 37189178 | 2023 | Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration. | 2 |
| 35088579 | 2022 | DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3. | 5 |
| 35088579 | 2022 | DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3. | 5 |
| 33308444 | 2021 | SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling. | 28 |
| 33308444 | 2021 | SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling. | 28 |
| 31742430 | 2020 | Activation of TGF-β1 Pathway by SCUBE3 Regulates TWIST1 Expression and Promotes Breast Cancer Progression. | 9 |
| 31991528 | 2020 | The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients. | 1 |
| 33274247 | 2020 | SCUBE3 Is Likely a Susceptibility Gene for Systemic Lupus Erythematosus for Chinese Populations. | 3 |
| 31742430 | 2020 | Activation of TGF-β1 Pathway by SCUBE3 Regulates TWIST1 Expression and Promotes Breast Cancer Progression. | 9 |
| 31991528 | 2020 | The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients. | 1 |
| 33274247 | 2020 | SCUBE3 Is Likely a Susceptibility Gene for Systemic Lupus Erythematosus for Chinese Populations. | 3 |
| 28238185 | 2017 | Can signal peptide-CUB-EGF domain-containing protein (SCUBE) levels be a marker of angiogenesis in patients with psoriasis? | 6 |
| 28238185 | 2017 | Can signal peptide-CUB-EGF domain-containing protein (SCUBE) levels be a marker of angiogenesis in patients with psoriasis? | 6 |
| 27259322 | 2015 | The Expression of HSPD1, SCUBE3, CXCL14 and Its Relations with the Prognosis in Osteosarcoma. | 15 |
Citation
Dessen P
SCUBE3 (signal peptide, CUB domain and EGF like domain containing 3)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52467/scube3
