Identity
HGNC
LOCATION
6p24.3
LOCUSID
ALIAS
CCAT,CTRCT13,GCNT2C,GCNT5,IGNT,II,NACGT1,NAGCT1,ULG3,bA360O19.2,bA421M1.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2651
MIM: 600429
HGNC: 4204
Ensembl: ENSG00000111846
Variants:
dbSNP: 2651
ClinVar: 2651
TCGA: ENSG00000111846
COSMIC: GCNT2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG | ko00601 |
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG | hsa00601 |
| Metabolic pathways | KEGG | hsa01100 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33660254 | 2021 | Melanoma-associated glycosyltransferase GCNT2 as an emerging biomarker and therapeutic target. | 4 |
| 33660254 | 2021 | Melanoma-associated glycosyltransferase GCNT2 as an emerging biomarker and therapeutic target. | 4 |
| 30575058 | 2019 | GCNT2 induces epithelial-mesenchymal transition and promotes migration and invasion in esophageal squamous cell carcinoma cells. | 7 |
| 31213534 | 2019 | I-branched carbohydrates as emerging effectors of malignant progression. | 17 |
| 30575058 | 2019 | GCNT2 induces epithelial-mesenchymal transition and promotes migration and invasion in esophageal squamous cell carcinoma cells. | 7 |
| 31213534 | 2019 | I-branched carbohydrates as emerging effectors of malignant progression. | 17 |
| 28542779 | 2017 | Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer. | 22 |
| 28542779 | 2017 | Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer. | 22 |
| 26678556 | 2016 | I-branching N-acetylglucosaminyltransferase regulates prostate cancer invasiveness by enhancing α5β1 integrin signaling. | 14 |
| 27936067 | 2016 | Deletion at the GCNT2 Locus Causes Autosomal Recessive Congenital Cataracts. | 5 |
| 26678556 | 2016 | I-branching N-acetylglucosaminyltransferase regulates prostate cancer invasiveness by enhancing α5β1 integrin signaling. | 14 |
| 27936067 | 2016 | Deletion at the GCNT2 Locus Causes Autosomal Recessive Congenital Cataracts. | 5 |
| 25750292 | 2015 | Aberrant methylation of GCNT2 is tightly related to lymph node metastasis of primary CRC. | 12 |
| 25750292 | 2015 | Aberrant methylation of GCNT2 is tightly related to lymph node metastasis of primary CRC. | 12 |
| 21761136 | 2012 | An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group. | 9 |
Citation
Dessen P
GCNT2 (glucosaminyl (N-acetyl) transferase 2 (I blood group))
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52469/gcnt2
