Identity
HGNC
LOCATION
12q12
LOCUSID
ALIAS
BAF200,CSS6,p200
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 196528
MIM: 609539
HGNC: 18037
Ensembl: ENSG00000189079
Variants:
dbSNP: 196528
ClinVar: 196528
TCGA: ENSG00000189079
COSMIC: ARID2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| RMTs methylate histone arginines | REACTOME | R-HSA-3214858 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38243407 | 2024 | ARID2, a milder cause of Coffin-Siris Syndrome? Broadening the phenotype with 17 additional individuals. | 0 |
| 38341515 | 2024 | ARID2 mutations may relay a distinct subset of cutaneous melanoma patients with different outcomes. | 0 |
| 38243407 | 2024 | ARID2, a milder cause of Coffin-Siris Syndrome? Broadening the phenotype with 17 additional individuals. | 0 |
| 38341515 | 2024 | ARID2 mutations may relay a distinct subset of cutaneous melanoma patients with different outcomes. | 0 |
| 36530029 | 2023 | miR-29a-5p regulates the malignant biological process of liver cancer cells through ARID2 regulation of EMT. | 1 |
| 36756859 | 2023 | ARID2, a rare cause of Coffin-Siris syndrome: A novel microdeletion at 12q12q13.11 causing severe short stature and literature review. | 1 |
| 38182156 | 2023 | Coffin-Siris Syndrome: Case Series of Three Patients and a Novel ARID2 Variant. | 0 |
| 36530029 | 2023 | miR-29a-5p regulates the malignant biological process of liver cancer cells through ARID2 regulation of EMT. | 1 |
| 36756859 | 2023 | ARID2, a rare cause of Coffin-Siris syndrome: A novel microdeletion at 12q12q13.11 causing severe short stature and literature review. | 1 |
| 38182156 | 2023 | Coffin-Siris Syndrome: Case Series of Three Patients and a Novel ARID2 Variant. | 0 |
| 35017665 | 2022 | BRD4 inhibition induces synthetic lethality in ARID2-deficient hepatocellular carcinoma by increasing DNA damage. | 6 |
| 35385731 | 2022 | Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma. | 13 |
| 35869277 | 2022 | ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications. | 4 |
| 36567903 | 2022 | USP2 Inhibits Lung Cancer Pathogenesis by Reducing ARID2 Protein Degradation via Ubiquitination. | 3 |
| 35017665 | 2022 | BRD4 inhibition induces synthetic lethality in ARID2-deficient hepatocellular carcinoma by increasing DNA damage. | 6 |
Citation
Dessen P
ARID2 (AT-rich interaction domain 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52470/arid2-(at-rich-interaction-domain-2)
