Identity
HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
CAPPA1,CAPZ,CAZ1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 829
MIM: 601580
HGNC: 1488
Ensembl: ENSG00000116489
Variants:
dbSNP: 829
ClinVar: 829
TCGA: ENSG00000116489
COSMIC: CAPZA1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116489 | ENST00000263168 | P52907 |
| ENSG00000116489 | ENST00000263168 | A0A024R0E5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36643863 | 2023 | Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis. | 9 |
| 36643863 | 2023 | Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis. | 9 |
| 34504078 | 2021 | A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks. | 42 |
| 34796874 | 2021 | Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors. | 7 |
| 34504078 | 2021 | A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks. | 42 |
| 34796874 | 2021 | Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors. | 7 |
| 30176157 | 2019 | CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy. | 29 |
| 30176157 | 2019 | CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy. | 29 |
| 28093067 | 2017 | CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma. | 32 |
| 28093067 | 2017 | CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma. | 32 |
| 26764407 | 2016 | Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2. | 11 |
| 26764407 | 2016 | Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2. | 11 |
| 26566078 | 2015 | Single-molecule visualization of a formin-capping protein 'decision complex' at the actin filament barbed end. | 57 |
| 26566078 | 2015 | Single-molecule visualization of a formin-capping protein 'decision complex' at the actin filament barbed end. | 57 |
| 23545944 | 2013 | Prognostic value of CAPZA1 overexpression in gastric cancer. | 18 |
Citation
Dessen P
CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-11-01
Online version: http://atlasgeneticsoncology.org/gene/52471/capza1-(capping-actin-protein-of-muscle-z-line-subunit-alpha-1)
