Identity
HGNC
LOCATION
7q21.3
LOCUSID
ALIAS
DNCI1,DNCIC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1780
MIM: 603772
HGNC: 2963
Ensembl: ENSG00000158560
Variants:
dbSNP: 1780
ClinVar: 1780
TCGA: ENSG00000158560
COSMIC: DYNC1I1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34679093 | 2021 | Bioinformatics analysis identifies DYNC1I1 as prognosis marker in male patients with liver hepatocellular carcinoma. | 5 |
| 34679093 | 2021 | Bioinformatics analysis identifies DYNC1I1 as prognosis marker in male patients with liver hepatocellular carcinoma. | 5 |
| 30250299 | 2019 | Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. | 11 |
| 31605449 | 2019 | TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis. | 8 |
| 30250299 | 2019 | Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. | 11 |
| 31605449 | 2019 | TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis. | 8 |
| 24459211 | 2014 | Next generation sequencing of chromosomal rearrangements in patients with split-hand/split-foot malformation provides evidence for DYNC1I1 exonic enhancers of DLX5/6 expression in humans. | 20 |
| 25015291 | 2014 | Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking. | 18 |
| 25231166 | 2014 | Deletions of exons with regulatory activity at the DYNC1I1 locus are associated with split-hand/split-foot malformation: array CGH screening of 134 unrelated families. | 21 |
| 24459211 | 2014 | Next generation sequencing of chromosomal rearrangements in patients with split-hand/split-foot malformation provides evidence for DYNC1I1 exonic enhancers of DLX5/6 expression in humans. | 20 |
| 25015291 | 2014 | Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking. | 18 |
| 25231166 | 2014 | Deletions of exons with regulatory activity at the DYNC1I1 locus are associated with split-hand/split-foot malformation: array CGH screening of 134 unrelated families. | 21 |
| 23960070 | 2013 | Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons. | 22 |
| 23960070 | 2013 | Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons. | 22 |
| 21763495 | 2011 | T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway. | 87 |
Citation
Dessen P
DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-11-01
Online version: http://atlasgeneticsoncology.org/gene/52486/dync1i1-(dynein-cytoplasmic-1-intermediate-chain-1)
