AFAP1L1 (actin filament associated protein 1 like 1)

2011-11-01  

Identity

HGNC
LOCATION
5q32
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 134265
MIM: 614410
HGNC: 26714
Ensembl: ENSG00000157510

Variants:

dbSNP: 134265
ClinVar: 134265
TCGA: ENSG00000157510
COSMIC: AFAP1L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157510ENST00000296721Q8TED9
ENSG00000157510ENST00000515000Q8TED9

Expression (GTEx)

0
10
20
30
40
50
60

References

Pubmed IDYearTitleCitations
213333782011AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes.18
233263072013The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).7
215161302011Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas.5
247234362014AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers.1
262120122016Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway.0
293231012018Actin Filament-Associated Protein 1-Like 1 Mediates Proliferation and Survival in Non-Small Cell Lung Cancer Cells.0

Citation

Dessen P

AFAP1L1 (actin filament associated protein 1 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-11-01

Online version: http://atlasgeneticsoncology.org/gene/52489/afap1l1-(actin-filament-associated-protein-1-like-1)