Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 134265
MIM: 614410
HGNC: 26714
Ensembl: ENSG00000157510
Variants:
dbSNP: 134265
ClinVar: 134265
TCGA: ENSG00000157510
COSMIC: AFAP1L1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000157510 | ENST00000296721 | Q8TED9 |
| ENSG00000157510 | ENST00000515000 | Q8TED9 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36631800 | 2023 | AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway. | 3 |
| 37737201 | 2023 | Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis. | 1 |
| 36631800 | 2023 | AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway. | 3 |
| 37737201 | 2023 | Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis. | 1 |
| 29323101 | 2018 | Actin Filament-Associated Protein 1-Like 1 Mediates Proliferation and Survival in Non-Small Cell Lung Cancer Cells. | 3 |
| 29323101 | 2018 | Actin Filament-Associated Protein 1-Like 1 Mediates Proliferation and Survival in Non-Small Cell Lung Cancer Cells. | 3 |
| 26212012 | 2016 | Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway. | 4 |
| 26212012 | 2016 | Regulation of sarcoma cell migration, invasion and invadopodia formation by AFAP1L1 through a phosphotyrosine-dependent pathway. | 4 |
| 24723436 | 2014 | AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers. | 3 |
| 24723436 | 2014 | AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers. | 3 |
| 23326307 | 2013 | The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1). | 9 |
| 23326307 | 2013 | The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1). | 9 |
| 21333378 | 2011 | AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes. | 26 |
| 21516130 | 2011 | Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas. | 7 |
| 21333378 | 2011 | AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes. | 26 |
Citation
Dessen P
AFAP1L1 (actin filament associated protein 1 like 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-11-01
Online version: http://atlasgeneticsoncology.org/gene/52489/afap1l1-(actin-filament-associated-protein-1-like-1)
