LCOR (ligand dependent nuclear receptor corepressor)

2012-01-01  

Identity

HGNC
LOCATION
10q24.1
LOCUSID
ALIAS
C10orf12,MLR2

Other Information

Locus ID:

NCBI: 84458
MIM: 607698
HGNC: 29503
Ensembl: ENSG00000196233

Variants:

dbSNP: 84458
ClinVar: 84458
TCGA: ENSG00000196233
COSMIC: LCOR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196233ENST00000286067A0A1P0AZG4
ENSG00000196233ENST00000356016Q96JN0
ENSG00000196233ENST00000371097Q96JN0
ENSG00000196233ENST00000371103Q96JN0
ENSG00000196233ENST00000421806Q96JN0
ENSG00000196233ENST00000540664Q96JN0

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
344109502021The Expression of NRIP1 and LCOR in Endometrioid Endometrial Cancer.2
344109502021The Expression of NRIP1 and LCOR in Endometrioid Endometrial Cancer.2
321574382020Regulation of LCoR and RIP140 expression in cervical intraepithelial neoplasia and correlation with CIN progression and dedifferentiation.4
321574382020Regulation of LCoR and RIP140 expression in cervical intraepithelial neoplasia and correlation with CIN progression and dedifferentiation.4
311865332019C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels.5
311865332019C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels.5
284143082017Complex regulation of LCoR signaling in breast cancer cells.19
285306572017Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis.60
284143082017Complex regulation of LCoR signaling in breast cancer cells.19
285306572017Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis.60
222776512012Ligand-dependent corepressor (LCoR) recruitment by Kruppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene.26
222776512012Ligand-dependent corepressor (LCoR) recruitment by Kruppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene.26
215658922011miR-615-3p promotes the phagocytic capacity of splenic macrophages by targeting ligand-dependent nuclear receptor corepressor in cirrhosis-related portal hypertension.23
218567472011Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase.28
215658922011miR-615-3p promotes the phagocytic capacity of splenic macrophages by targeting ligand-dependent nuclear receptor corepressor in cirrhosis-related portal hypertension.23

Citation

Dessen P

LCOR (ligand dependent nuclear receptor corepressor)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52507/lcor-(ligand-dependent-nuclear-receptor-corepressor)