CADPS (calcium dependent secretion activator)

2011-12-01  

Identity

HGNC
CADPS
LOCATION
3p14.2
LOCUSID
8618
ALIAS
CADPS1,CAPS,CAPS1,UNC-31
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8618
MIM: 604667
HGNC: 1426
Ensembl: ENSG00000163618

Variants:

dbSNP: 8618
ClinVar: 8618
TCGA: ENSG00000163618
COSMIC: CADPS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163618ENST00000283269Q9ULU8
ENSG00000163618ENST00000357948Q9ULU8
ENSG00000163618ENST00000383710Q9ULU8
ENSG00000163618ENST00000466621H7C4K9
ENSG00000163618ENST00000468271H7C4P2
ENSG00000163618ENST00000473635H7C538
ENSG00000163618ENST00000490353Q9ULU8
ENSG00000163618ENST00000491424H7C4T6
ENSG00000163618ENST00000542833H0YFP0
ENSG00000163618ENST00000612439F1T0E5
ENSG00000163618ENST00000613879A0A0C4DGY2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
217988482011Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma.22
158576092005Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS).15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
238013302013Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1.5
216016102011Expression of Ca²⁺-dependent activator protein for secretion 2 is increased in the brains of schizophrenic patients.4
307420662019CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation.4
316382362019Exosomes isolated from CAPS1‑overexpressing colorectal cancer cells promote cell migration.0

Citation

Dessen P

CADPS (calcium dependent secretion activator)

Atlas Genet Cytogenet Oncol Haematol. 2011-12-01

Online version: http://atlasgeneticsoncology.org/gene/52513/cadps-(calcium-dependent-secretion-activator)