ILF2 (interleukin enhancer binding factor 2)

2012-01-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
NF45,PRO3063
FUSION GENES

Other Information

Locus ID:

NCBI: 3608
MIM: 603181
HGNC: 6037
Ensembl: ENSG00000143621

Variants:

dbSNP: 3608
ClinVar: 3608
TCGA: ENSG00000143621
COSMIC: ILF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143621ENST00000361891Q12905
ENSG00000143621ENST00000361891F4ZW62
ENSG00000143621ENST00000368681A0A0A0MRL0
ENSG00000143621ENST00000368684X6R6Z1
ENSG00000143621ENST00000615950B4DY09

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386225222024Integrating trans-omics, cellular experiments and clinical validation to identify ILF2 as a diagnostic serum biomarker and therapeutic target in gastric cancer.0
386225222024Integrating trans-omics, cellular experiments and clinical validation to identify ILF2 as a diagnostic serum biomarker and therapeutic target in gastric cancer.0
370472322023NUSAP1 Binds ILF2 to Modulate R-Loop Accumulation and DNA Damage in Prostate Cancer.4
370472322023NUSAP1 Binds ILF2 to Modulate R-Loop Accumulation and DNA Damage in Prostate Cancer.4
351451872022ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells.5
353336832022Serine hydroxymethyltransferase 2 (SHMT2) potentiates the aggressive process of oral squamous cell carcinoma by binding to interleukin enhancer-binding factor 2 (ILF2).9
351451872022ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells.5
353336832022Serine hydroxymethyltransferase 2 (SHMT2) potentiates the aggressive process of oral squamous cell carcinoma by binding to interleukin enhancer-binding factor 2 (ILF2).9
327095322021Deletion of interleukin enhancer binding factor 2 (ILF2) resulted in defective biliary development and bile flow blockage.3
327483302021Interleukin Enhancer Binding Factor 2 Regulates Cell Viability and Apoptosis of Human Brain Vascular Smooth Muscle Cells.3
341532992021CRNDE-h transcript/miR-136-5p axis regulates interleukin enhancer binding factor 2 expression to promote hepatocellular carcinoma cell proliferation.2
327095322021Deletion of interleukin enhancer binding factor 2 (ILF2) resulted in defective biliary development and bile flow blockage.3
327483302021Interleukin Enhancer Binding Factor 2 Regulates Cell Viability and Apoptosis of Human Brain Vascular Smooth Muscle Cells.3
341532992021CRNDE-h transcript/miR-136-5p axis regulates interleukin enhancer binding factor 2 expression to promote hepatocellular carcinoma cell proliferation.2
323882722020Circular RNA 406961 interacts with ILF2 to regulate PM(2.5)-induced inflammatory responses in human bronchial epithelial cells via activation of STAT3/JNK pathways.22

Citation

Dessen P

ILF2 (interleukin enhancer binding factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52546/ilf2-(interleukin-enhancer-binding-factor-2)