ATAD5 (ATPase family AAA domain containing 5)

2012-01-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
C17orf41,ELG1,FRAG1
FUSION GENES

Other Information

Locus ID:

NCBI: 79915
MIM: 609534
HGNC: 25752
Ensembl: ENSG00000176208

Variants:

dbSNP: 79915
ClinVar: 79915
TCGA: ENSG00000176208
COSMIC: ATAD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176208ENST00000321990Q96QE3
ENSG00000176208ENST00000578295A0A075B754

Expression (GTEx)

0
5
10
15
20

References

Pubmed IDYearTitleCitations
366750812023Effects of Defective Unloading and Recycling of PCNA Revealed by the Analysis of ELG1 Mutants.1
377394272023Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination.0
366750812023Effects of Defective Unloading and Recycling of PCNA Revealed by the Analysis of ELG1 Mutants.1
377394272023Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination.0
347187492021Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair.11
347187492021Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair.11
325423382020ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork.34
325948262020ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1.6
325423382020ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork.34
325948262020ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1.6
318440452019ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress.22
318440452019ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress.22
270454772016Rare ATAD5 missense variants in breast and ovarian cancer patients.13
270454772016Rare ATAD5 missense variants in breast and ovarian cancer patients.13
257951252015Elg1, a central player in genome stability.11

Citation

Dessen P

ATAD5 (ATPase family AAA domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52556/atad5-(atpase-family-aaa-domain-containing-5)