PARPBP (PARP1 binding protein)

2012-01-01  

Identity

HGNC
LOCATION
12q23.2
LOCUSID
ALIAS
AROM,C12orf48,PARI
FUSION GENES

Other Information

Locus ID:

NCBI: 55010
MIM: 613687
HGNC: 26074
Ensembl: ENSG00000185480

Variants:

dbSNP: 55010
ClinVar: 55010
TCGA: ENSG00000185480
COSMIC: PARPBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185480ENST00000327680Q9NWS1
ENSG00000185480ENST00000392909G8JLI2
ENSG00000185480ENST00000392911Q9NWS1
ENSG00000185480ENST00000392911A0A024RBG0
ENSG00000185480ENST00000412715A0A0C4DG30
ENSG00000185480ENST00000417507J3KQY3
ENSG00000185480ENST00000457614H0Y6B3
ENSG00000185480ENST00000537257Q9NWS1
ENSG00000185480ENST00000541394B4DZ31
ENSG00000185480ENST00000543784B4DT40

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360566902022SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.9
360566902022SNORA70E promotes the occurrence and development of ovarian cancer through pseudouridylation modification of RAP1B and alternative splicing of PARPBP.9
309499052019Overexpression of PARPBP Correlates with Tumor Progression and Poor Prognosis in Hepatocellular Carcinoma.13
309676292019PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells.7
316111992019Poly (ADP-ribose) polymerase-1 Binding Protein Facilitates Lung Adenocarcinoma Cell Proliferation and Correlates with Poor Prognosis.2
309499052019Overexpression of PARPBP Correlates with Tumor Progression and Poor Prognosis in Hepatocellular Carcinoma.13
309676292019PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells.7
316111992019Poly (ADP-ribose) polymerase-1 Binding Protein Facilitates Lung Adenocarcinoma Cell Proliferation and Correlates with Poor Prognosis.2
298053042018PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.6
298053042018PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development.6
288940292017PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.6
288940292017PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.6
267928952016The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.21
267928952016The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.21
234367992013PARI overexpression promotes genomic instability and pancreatic tumorigenesis.17

Citation

Dessen P

PARPBP (PARP1 binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52559/parpbp-(parp1-binding-protein)