TFAP2E (transcription factor AP-2 epsilon)

2012-01-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
AP-2epsilon,AP2E

Other Information

Locus ID:

NCBI: 339488
MIM: 614428
HGNC: 30774
Ensembl: ENSG00000116819

Variants:

dbSNP: 339488
ClinVar: 339488
TCGA: ENSG00000116819
COSMIC: TFAP2E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116819ENST00000373235Q6VUC0

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsREACTOMER-HSA-8864260
Activation of the TFAP2 (AP-2) family of transcription factorsREACTOMER-HSA-8866907
Negative regulation of activity of TFAP2 (AP-2) family transcription factorsREACTOMER-HSA-8866904

References

Pubmed IDYearTitleCitations
387731082024Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanoma.0
387731082024Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanoma.0
311155332019TFAP2E methylation promotes 5‑fluorouracil resistance via exosomal miR‑106a‑5p and miR‑421 in gastric cancer MGC‑803 cells.19
311155332019TFAP2E methylation promotes 5‑fluorouracil resistance via exosomal miR‑106a‑5p and miR‑421 in gastric cancer MGC‑803 cells.19
295351272018TFAP2E Methylation and Expression Status Does Not Predict Response to 5-FU-based Chemotherapy in Colorectal Cancer.7
295351272018TFAP2E Methylation and Expression Status Does Not Predict Response to 5-FU-based Chemotherapy in Colorectal Cancer.7
282601052017Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells.6
282601052017Depletion of TFAP2E attenuates adriamycin-mediated apoptosis in human neuroblastoma cells.6
258104912016Transcription Factor AP2ε: A Potential Predictor of Chemoresistance in Patients With Gastric Cancer.4
258104912016Transcription Factor AP2ε: A Potential Predictor of Chemoresistance in Patients With Gastric Cancer.4
249969902014TFAP2E hypermethylation was associated with survival advantage in patients with colorectal cancer.9
249969902014TFAP2E hypermethylation was associated with survival advantage in patients with colorectal cancer.9
233316252013The transcription factor activating enhancer-binding protein epsilon (AP-2ε) regulates the core promoter of type II collagen (COL2A1).6
233316252013The transcription factor activating enhancer-binding protein epsilon (AP-2ε) regulates the core promoter of type II collagen (COL2A1).6
222168412012TFAP2E-DKK4 and chemoresistance in colorectal cancer.72

Citation

Dessen P

TFAP2E (transcription factor AP-2 epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52562/tfap2e-(transcription-factor-ap-2-epsilon)