CLEC11A (C-type lectin domain containing 11A)

2012-01-01  

Identity

HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
CLECSF3,LSLCL,P47,SCGF

Other Information

Locus ID:

NCBI: 6320
MIM: 604713
HGNC: 10576
Ensembl: ENSG00000105472

Variants:

dbSNP: 6320
ClinVar: 6320
TCGA: ENSG00000105472
COSMIC: CLEC11A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105472ENST00000250340Q9Y240
ENSG00000105472ENST00000599973M0R081
ENSG00000105472ENST00000617718V9H0X6

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
152342252004Stem cell factor and c-kit are expressed by and may affect vascular SMCs through an autocrine pathway.27
119202662001Stem cell growth factor: in situ hybridization analysis on the gene expression, molecular characterization and in vitro proliferative activity of a recombinant preparation on primitive hematopoietic progenitor cells.18
198843282010A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.14
264405922015Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders.14
279769992016Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.13
195282162009Suppression of a novel hematopoietic mediator in children with severe malarial anemia.10
265640032015Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques.9
147468052003Recombinant human (rh) stem cell factor and rhIL-4 stimulate differentiation and proliferation of CD3+ cells from umbilical cord blood and CD3+ cells enhance FcepsilonR1 expression on fetal liver-derived mast cells in the presence of rhIL-4.3
194162732009Association study between keratinocyte-derived growth factor gene polymorphisms and susceptibility to vitiligo vulgaris in a Taiwanese population: potential involvement of stem cell factor.2
219431292011Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy.1

Citation

Dessen P

CLEC11A (C-type lectin domain containing 11A)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52572/clec11a-(c-type-lectin-domain-containing-11a)