Identity
HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
AOS1,HSPC140,SUA1,UBLE1A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10055
MIM: 613294
HGNC: 30660
Ensembl: ENSG00000142230
Variants:
dbSNP: 10055
ClinVar: 10055
TCGA: ENSG00000142230
COSMIC: SAE1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38351014 | 2024 | ROS-mediated up-regulation of SAE1 by Helicobacter pylori promotes human gastric tumor genesis and progression. | 1 |
| 38351014 | 2024 | ROS-mediated up-regulation of SAE1 by Helicobacter pylori promotes human gastric tumor genesis and progression. | 1 |
| 36748193 | 2023 | Increased Small Ubiquitin-like Modifier-Activating Enzyme SAE1 Promotes Hepatocellular Carcinoma by Enhancing mTOR SUMOylation. | 3 |
| 37705041 | 2023 | Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation. | 2 |
| 36748193 | 2023 | Increased Small Ubiquitin-like Modifier-Activating Enzyme SAE1 Promotes Hepatocellular Carcinoma by Enhancing mTOR SUMOylation. | 3 |
| 37705041 | 2023 | Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation. | 2 |
| 33477333 | 2021 | SUMO-Activating Enzyme Subunit 1 (SAE1) Is a Promising Diagnostic Cancer Metabolism Biomarker of Hepatocellular Carcinoma. | 15 |
| 34414886 | 2021 | An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. | 12 |
| 33477333 | 2021 | SUMO-Activating Enzyme Subunit 1 (SAE1) Is a Promising Diagnostic Cancer Metabolism Biomarker of Hepatocellular Carcinoma. | 15 |
| 34414886 | 2021 | An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. | 12 |
| 32249212 | 2020 | SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation. | 11 |
| 32938830 | 2020 | Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes. | 14 |
| 32249212 | 2020 | SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation. | 11 |
| 32938830 | 2020 | Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes. | 14 |
| 31345225 | 2019 | SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways. | 25 |
Citation
Dessen P
SAE1 (SUMO1 activating enzyme subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-02-01
Online version: http://atlasgeneticsoncology.org/gene/52591/sae1-(sumo1-activating-enzyme-subunit-1)
