KIAA1549 (KIAA1549)

2012-03-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
RP86
FUSION GENES

Other Information

Locus ID:

NCBI: 57670
MIM: 613344
HGNC: 22219
Ensembl: ENSG00000122778

Variants:

dbSNP: 57670
ClinVar: 57670
TCGA: ENSG00000122778
COSMIC: KIAA1549

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122778ENST00000422774Q9HCM3
ENSG00000122778ENST00000440172Q9HCM3

Expression (GTEx)

0
1
2
3
4
5

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Oncogenic MAPK signalingREACTOMER-HSA-6802957
Signaling by BRAF and RAF fusionsREACTOMER-HSA-6802952

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371408132024KIAA1549 promotes the development and chemoresistance of colorectal cancer by upregulating ERCC2.0
371408132024KIAA1549 promotes the development and chemoresistance of colorectal cancer by upregulating ERCC2.0
336410742021Concomitant KIAA1549-BRAF fusion and IDH mutation in Pediatric spinal cord astrocytoma: a case report and literature review.2
336410742021Concomitant KIAA1549-BRAF fusion and IDH mutation in Pediatric spinal cord astrocytoma: a case report and literature review.2
305040642019KIAA1549-BRAF Expression Establishes a Permissive Tumor Microenvironment Through NFκB-Mediated CCL2 Production.21
305040642019KIAA1549-BRAF Expression Establishes a Permissive Tumor Microenvironment Through NFκB-Mediated CCL2 Production.21
261159612016Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549-BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification.18
269450352016Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status.14
261159612016Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549-BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification.18
269450352016Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status.14
257944452015Oncogenic KIAA1549-BRAF fusion with activation of the MAPK/ERK pathway in pediatric oligodendrogliomas.13
260835712015KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.40
257944452015Oncogenic KIAA1549-BRAF fusion with activation of the MAPK/ERK pathway in pediatric oligodendrogliomas.13
260835712015KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.40
245292092014Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups.15

Citation

Dessen P

KIAA1549 (KIAA1549)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52621