KATNA1 (katanin catalytic subunit A1)

2012-03-01   Dessen P  

Identity

HGNC
KATNA1
LOCATION
6q25.1
LOCUSID
11104
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11104
MIM: 606696
HGNC: 6216
Ensembl: ENSG00000186625

Variants:

dbSNP: 11104
ClinVar: 11104
TCGA: ENSG00000186625
COSMIC: KATNA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186625ENST00000335643O75449
ENSG00000186625ENST00000335647O75449
ENSG00000186625ENST00000367411O75449
ENSG00000186625ENST00000420200B7ZBC9
ENSG00000186625ENST00000444282B7ZBC8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
358685572022SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth.2
358685572022SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth.2
337826142021A chemical genetics approach to examine the functions of AAA proteins.3
337826142021A chemical genetics approach to examine the functions of AAA proteins.3
326313342020Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer.6
332744992020Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival.3
326313342020Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer.6
332744992020Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival.3
306993602019Structural and Molecular Basis for Katanin-Mediated Severing of Glutamylated Microtubules.26
307899742019Elk1 affects katanin and spastin proteins via differential transcriptional and post-transcriptional regulations.4
306993602019Structural and Molecular Basis for Katanin-Mediated Severing of Glutamylated Microtubules.26
307899742019Elk1 affects katanin and spastin proteins via differential transcriptional and post-transcriptional regulations.4
301761232018Creation and testing of a new, local microtubule-disruption tool based on the microtubule-severing enzyme, katanin p60.1
301761232018Creation and testing of a new, local microtubule-disruption tool based on the microtubule-severing enzyme, katanin p60.1
283860212017CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin.10

Citation

Dessen P

KATNA1 (katanin catalytic subunit A1)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52633/katna1-(katanin-catalytic-subunit-a1)