KATNA1 (katanin catalytic subunit A1)

2012-03-01  

Identity

HGNC
LOCATION
6q25.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 11104
MIM: 606696
HGNC: 6216
Ensembl: ENSG00000186625

Variants:

dbSNP: 11104
ClinVar: 11104
TCGA: ENSG00000186625
COSMIC: KATNA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186625ENST00000335643O75449
ENSG00000186625ENST00000335647O75449
ENSG00000186625ENST00000367411O75449
ENSG00000186625ENST00000420200B7ZBC9
ENSG00000186625ENST00000444282B7ZBC8

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
284369672017Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.30
232720562012Spastin's microtubule-binding properties and comparison to katanin.21
203390002010A common substrate recognition mode conserved between katanin p60 and VPS4 governs microtubule severing and membrane skeleton reorganization.18
266828132015Katanin Severing and Binding Microtubules Are Inhibited by Tubulin Carboxy Tails.17
205089832011Centrosome-related genes, genetic variation, and risk of breast cancer.16
184903572008LAPSER1/LZTS2: a pluripotent tumor suppressor linked to the inhibition of katanin-mediated microtubule severing.13
216817752012Aberrant expression of katanin p60 in prostate cancer bone metastasis.8
223250072012Effect of Ca2+ on the microtubule-severing enzyme p60-katanin. Insight into the substrate-dependent activation mechanism.6
306993602019Structural and Molecular Basis for Katanin-Mediated Severing of Glutamylated Microtubules.5
283860212017CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin.4

Citation

Dessen P

KATNA1 (katanin catalytic subunit A1)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52633/katna1-(katanin-catalytic-subunit-a1)