Identity
HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
Hsh155,MDS,PRP10,PRPF10,SAP155,SF3b155
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23451
MIM: 605590
HGNC: 10768
Ensembl: ENSG00000115524
Variants:
dbSNP: 23451
ClinVar: 23451
TCGA: ENSG00000115524
COSMIC: SF3B1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37921711 | 2024 | Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts. | 0 |
| 38517966 | 2024 | SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia. | 0 |
| 38521065 | 2024 | Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape. | 4 |
| 38632316 | 2024 | Mutations in the splicing factor SF3B1 are linked to frequent emergence of HLA-DR(low/neg) monocytes in lower-risk myelodysplastic neoplasms. | 0 |
| 37921711 | 2024 | Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts. | 0 |
| 38517966 | 2024 | SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia. | 0 |
| 38521065 | 2024 | Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape. | 4 |
| 38632316 | 2024 | Mutations in the splicing factor SF3B1 are linked to frequent emergence of HLA-DR(low/neg) monocytes in lower-risk myelodysplastic neoplasms. | 0 |
| 36411516 | 2023 | Prognostic correlation of NOTCH1 and SF3B1 mutations with chromosomal abnormalities in chronic lymphocytic leukemia patients. | 2 |
| 36944332 | 2023 | m(6)A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis. | 7 |
| 37026485 | 2023 | CDK12/13 promote splicing of proximal introns by enhancing the interaction between RNA polymerase II and the splicing factor SF3B1. | 8 |
| 37263951 | 2023 | [Clinical features of SF3B1 mutation in patients with myelodysplastic syndrome with excess blasts]. | 0 |
| 37408496 | 2023 | Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B1. | 0 |
| 37511096 | 2023 | SF3B1 Mutations Are Associated with Resistance to Non-Genotoxic MDM2 Inhibition in Chronic Lymphocytic Leukemia. | 2 |
| 37524790 | 2023 | SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. | 6 |
Citation
Dessen P
SF3B1 (splicing factor 3b subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-03-01
Online version: http://atlasgeneticsoncology.org/gene/52653
