Identity
HGNC
LOCATION
18q21.33
LOCUSID
ALIAS
MIG1,SKD1,SKD1B,VPS4-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9525
MIM: 609983
HGNC: 10895
Ensembl: ENSG00000119541
Variants:
dbSNP: 9525
ClinVar: 9525
TCGA: ENSG00000119541
COSMIC: VPS4B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119541 | ENST00000238497 | O75351 |
| ENSG00000119541 | ENST00000238497 | A0A024R2C5 |
| ENSG00000119541 | ENST00000588059 | K7EL71 |
| ENSG00000119541 | ENST00000591519 | K7EKZ3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37154262 | 2024 | p-AKT/VPS4B regulates the small extracellular vesicle size in venous malformation endothelial cells. | 0 |
| 37154262 | 2024 | p-AKT/VPS4B regulates the small extracellular vesicle size in venous malformation endothelial cells. | 0 |
| 36042696 | 2022 | Analysis of individual HIV-1 budding event using fast AFM reveals a multiplexed role for VPS4. | 5 |
| 36042696 | 2022 | Analysis of individual HIV-1 budding event using fast AFM reveals a multiplexed role for VPS4. | 5 |
| 31930723 | 2020 | Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer. | 19 |
| 32737282 | 2020 | VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I. | 3 |
| 33326793 | 2020 | Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. | 17 |
| 31930723 | 2020 | Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer. | 19 |
| 32737282 | 2020 | VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I. | 3 |
| 33326793 | 2020 | Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. | 17 |
| 31218890 | 2019 | Vacuolar protein sorting 4B regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells through the Wnt-β-catenin signalling pathway. | 8 |
| 31218890 | 2019 | Vacuolar protein sorting 4B regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells through the Wnt-β-catenin signalling pathway. | 8 |
| 28744712 | 2017 | Vacuolar Protein Sorting 4B (VPS4B) Regulates Apoptosis of Chondrocytes via p38 Mitogen-Activated Protein Kinases (MAPK) in Osteoarthritis. | 7 |
| 28744712 | 2017 | Vacuolar Protein Sorting 4B (VPS4B) Regulates Apoptosis of Chondrocytes via p38 Mitogen-Activated Protein Kinases (MAPK) in Osteoarthritis. | 7 |
| 27247351 | 2016 | A splicing mutation in VPS4B causes dentin dysplasia I. | 13 |
Citation
Dessen P
VPS4B (vacuolar protein sorting 4 homolog B)
Atlas Genet Cytogenet Oncol Haematol. 2012-04-01
Online version: http://atlasgeneticsoncology.org/gene/52680/vps4b-(vacuolar-protein-sorting-4-homolog-b)
