Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 693123
MIM: 613132
HGNC: 32794
Ensembl: ENSG00000207728
miRBase:
Variants:
dbSNP: 693123
ClinVar: 693123
TCGA: ENSG00000207728
COSMIC: MIR449B
RNA/Proteins
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443937 | Drug Toxicity | Disease | VariantAnnotation | not associated | PD | ||
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Disease | VariantAnnotation | not associated | PD | ||
| PA448492 | asparaginase | Chemical | VariantAnnotation | not associated | PD | ||
| PA449165 | cyclophosphamide | Chemical | VariantAnnotation | not associated | PD | ||
| PA449177 | cytarabine | Chemical | VariantAnnotation | not associated | PD | ||
| PA449212 | daunorubicin | Chemical | VariantAnnotation | not associated | PD | ||
| PA450379 | mercaptopurine | Chemical | VariantAnnotation | not associated | PD | ||
| PA450428 | methotrexate | Chemical | VariantAnnotation | not associated | PD | ||
| PA451100 | prednisone | Chemical | VariantAnnotation | not associated | PD | ||
| PA451879 | vincristine | Chemical | VariantAnnotation | not associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35650603 | 2022 | CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2. | 27 |
| 35650603 | 2022 | CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2. | 27 |
| 32074771 | 2020 | [Effect of CASC19 on proliferation, apoptosis and radiation sensitivity of cervical cancer cells by regulating miR-449b-5p expression]. | 1 |
| 32471413 | 2020 | MiR-449b-5p targets lncRNA PSMG3-AS1 to suppress cancer cell proliferation in lung adenocarcinoma. | 9 |
| 32495889 | 2020 | MiR-449b-5p inhibits human glioblastoma cell proliferation by inactivating WNT2B/Wnt/β-catenin signaling pathway. | 7 |
| 32720593 | 2020 | SNHG7 Facilitates Glioblastoma Progression by Functioning as a Molecular Sponge for MicroRNA-449b-5p and Thereby Increasing MYCN Expression. | 4 |
| 33275219 | 2020 | MDM4 is targeted by miR-449b-5p to promote the proliferation of endometrial carcinoma. | 2 |
| 32074771 | 2020 | [Effect of CASC19 on proliferation, apoptosis and radiation sensitivity of cervical cancer cells by regulating miR-449b-5p expression]. | 1 |
| 32471413 | 2020 | MiR-449b-5p targets lncRNA PSMG3-AS1 to suppress cancer cell proliferation in lung adenocarcinoma. | 9 |
| 32495889 | 2020 | MiR-449b-5p inhibits human glioblastoma cell proliferation by inactivating WNT2B/Wnt/β-catenin signaling pathway. | 7 |
| 32720593 | 2020 | SNHG7 Facilitates Glioblastoma Progression by Functioning as a Molecular Sponge for MicroRNA-449b-5p and Thereby Increasing MYCN Expression. | 4 |
| 33275219 | 2020 | MDM4 is targeted by miR-449b-5p to promote the proliferation of endometrial carcinoma. | 2 |
| 30738779 | 2019 | MicroRNA-449b-5p suppresses the growth and invasion of breast cancer cells via inhibiting CREPT-mediated Wnt/β-catenin signaling. | 23 |
| 31103631 | 2019 | MiR-449b-5p regulates cell proliferation, migration and radioresistance in cervical cancer by interacting with the transcription suppressor FOXP1. | 15 |
| 31350893 | 2019 | MicroRNA-449b-5p suppresses cell proliferation, migration and invasion by targeting TPD52 in nasopharyngeal carcinoma. | 11 |
Citation
Dessen P
MIR449B (microRNA 449b)
Atlas Genet Cytogenet Oncol Haematol. 2012-04-01
Online version: http://atlasgeneticsoncology.org/gene/52683/mir449b-(microrna-449b)
