MIR449B (microRNA 449b)

2012-04-01 Affiliation

Identity

HGNC

MIR449B

LOCATION

5q11.2

LOCUSID

693123

ALIAS

MIRN449B,mir-449b

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 693123
MIM: 613132
HGNC: 32794
Ensembl: ENSG00000207728
miRBase:

Variants:

dbSNP: 693123
ClinVar: 693123
TCGA: ENSG00000207728
COSMIC: MIR449B

RNA/Proteins

PharmGKB

Entity ID	Name	Type	Evidence	Association	PD
PA443937	Drug Toxicity	Disease	VariantAnnotation	not associated	PD
PA446155	Precursor Cell Lymphoblastic Leukemia-Lymphoma	Disease	VariantAnnotation	not associated	PD
PA448492	asparaginase	Chemical	VariantAnnotation	not associated	PD
PA449165	cyclophosphamide	Chemical	VariantAnnotation	not associated	PD
PA449177	cytarabine	Chemical	VariantAnnotation	not associated	PD
PA449212	daunorubicin	Chemical	VariantAnnotation	not associated	PD
PA450379	mercaptopurine	Chemical	VariantAnnotation	not associated	PD
PA450428	methotrexate	Chemical	VariantAnnotation	not associated	PD
PA451100	prednisone	Chemical	VariantAnnotation	not associated	PD
PA451879	vincristine	Chemical	VariantAnnotation	not associated	PD

References

Pubmed ID	Year	Title	Citations
35650603	2022	CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2.	27
35650603	2022	CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2.	27
32074771	2020	[Effect of CASC19 on proliferation, apoptosis and radiation sensitivity of cervical cancer cells by regulating miR-449b-5p expression].	1
32471413	2020	MiR-449b-5p targets lncRNA PSMG3-AS1 to suppress cancer cell proliferation in lung adenocarcinoma.	9
32495889	2020	MiR-449b-5p inhibits human glioblastoma cell proliferation by inactivating WNT2B/Wnt/β-catenin signaling pathway.	7
32720593	2020	SNHG7 Facilitates Glioblastoma Progression by Functioning as a Molecular Sponge for MicroRNA-449b-5p and Thereby Increasing MYCN Expression.	4
33275219	2020	MDM4 is targeted by miR-449b-5p to promote the proliferation of endometrial carcinoma.	2
32074771	2020	[Effect of CASC19 on proliferation, apoptosis and radiation sensitivity of cervical cancer cells by regulating miR-449b-5p expression].	1
32471413	2020	MiR-449b-5p targets lncRNA PSMG3-AS1 to suppress cancer cell proliferation in lung adenocarcinoma.	9
32495889	2020	MiR-449b-5p inhibits human glioblastoma cell proliferation by inactivating WNT2B/Wnt/β-catenin signaling pathway.	7
32720593	2020	SNHG7 Facilitates Glioblastoma Progression by Functioning as a Molecular Sponge for MicroRNA-449b-5p and Thereby Increasing MYCN Expression.	4
33275219	2020	MDM4 is targeted by miR-449b-5p to promote the proliferation of endometrial carcinoma.	2
30738779	2019	MicroRNA-449b-5p suppresses the growth and invasion of breast cancer cells via inhibiting CREPT-mediated Wnt/β-catenin signaling.	23
31103631	2019	MiR-449b-5p regulates cell proliferation, migration and radioresistance in cervical cancer by interacting with the transcription suppressor FOXP1.	15
31350893	2019	MicroRNA-449b-5p suppresses cell proliferation, migration and invasion by targeting TPD52 in nasopharyngeal carcinoma.	11

Citation

Dessen P

MIR449B (microRNA 449b)

Atlas Genet Cytogenet Oncol Haematol. 2012-04-01

Online version: http://atlasgeneticsoncology.org/gene/52683/mir449b-(microrna-449b)