PAAF1 (proteasomal ATPase associated factor 1)

2012-05-01   Dessen P  

Identity

HGNC
PAAF1
LOCATION
11q13.4
LOCUSID
80227
ALIAS
PAAF,Rpn14,WDR71
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80227
HGNC: 25687
Ensembl: ENSG00000175575

Variants:

dbSNP: 80227
ClinVar: 80227
TCGA: ENSG00000175575
COSMIC: PAAF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175575ENST00000310571Q9BRP4
ENSG00000175575ENST00000376384Q9BRP4
ENSG00000175575ENST00000376384A0A024R5N4
ENSG00000175575ENST00000504441F5H103
ENSG00000175575ENST00000535604Q9BRP4
ENSG00000175575ENST00000536003Q9BRP4
ENSG00000175575ENST00000536003A0A024R5N4
ENSG00000175575ENST00000536582F5H5D4
ENSG00000175575ENST00000540659H0YGB1
ENSG00000175575ENST00000541951Q9BRP4
ENSG00000175575ENST00000542293F5H3E9
ENSG00000175575ENST00000543814F5H3I1
ENSG00000175575ENST00000544552Q9BRP4
ENSG00000175575ENST00000544552A0A024R5N4
ENSG00000175575ENST00000544909F5H0C4
ENSG00000175575ENST00000546039F5H0F7

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
344466012021Identification of a quality-control factor that monitors failures during proteasome assembly.12
344466012021Identification of a quality-control factor that monitors failures during proteasome assembly.12
223161382012Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR.12
223161382012Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR.12
158314872005Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases.22
158314872005Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases.22

Citation

Dessen P

PAAF1 (proteasomal ATPase associated factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-05-01

Online version: http://atlasgeneticsoncology.org/gene/52700/paaf1-(proteasomal-atpase-associated-factor-1)