Identity
HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
PR264,SC-35,SC35,SFRS2,SFRS2A,SRp30b
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6427
MIM: 600813
HGNC: 10783
Ensembl: ENSG00000161547
Variants:
dbSNP: 6427
ClinVar: 6427
TCGA: ENSG00000161547
COSMIC: SRSF2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38678322 | 2024 | [SRSF2 promotes glioblastoma cell proliferation by inducing alternative splicing of FSP1 and inhibiting ferroptosis]. | 0 |
| 38713535 | 2024 | A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies. | 1 |
| 38678322 | 2024 | [SRSF2 promotes glioblastoma cell proliferation by inducing alternative splicing of FSP1 and inhibiting ferroptosis]. | 0 |
| 38713535 | 2024 | A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies. | 1 |
| 37335045 | 2023 | Serine-arginine splicing factor 2 promotes oesophageal cancer progression by regulating alternative splicing of interferon regulatory factor 3. | 0 |
| 37344641 | 2023 | Clinical and prognostic profile of SRSF2 and related spliceosome mutations in patients with acute myeloid leukemia. | 1 |
| 37354804 | 2023 | Co-occurring mutations in ASXL1, SRSF2, and SETBP1 define a subset of myelodysplastic/ myeloproliferative neoplasm with neutrophilia. | 0 |
| 37867192 | 2023 | SRSF2 is required for mRNA splicing during spermatogenesis. | 1 |
| 38065062 | 2023 | SRSF2 plays an unexpected role as reader of m(5)C on mRNA, linking epitranscriptomics to cancer. | 2 |
| 37335045 | 2023 | Serine-arginine splicing factor 2 promotes oesophageal cancer progression by regulating alternative splicing of interferon regulatory factor 3. | 0 |
| 37344641 | 2023 | Clinical and prognostic profile of SRSF2 and related spliceosome mutations in patients with acute myeloid leukemia. | 1 |
| 37354804 | 2023 | Co-occurring mutations in ASXL1, SRSF2, and SETBP1 define a subset of myelodysplastic/ myeloproliferative neoplasm with neutrophilia. | 0 |
| 37867192 | 2023 | SRSF2 is required for mRNA splicing during spermatogenesis. | 1 |
| 38065062 | 2023 | SRSF2 plays an unexpected role as reader of m(5)C on mRNA, linking epitranscriptomics to cancer. | 2 |
| 34464972 | 2022 | Genome-wide screening identifies cell-cycle control as a synthetic lethal pathway with SRSF2P95H mutation. | 6 |
Citation
Dessen P
SRSF2 (serine and arginine rich splicing factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-06-01
Online version: http://atlasgeneticsoncology.org/gene/52737/srsf2-(serine-and-arginine-rich-splicing-factor-2)
