PRSS23 (serine protease 23)

2012-06-01  

Identity

HGNC
PRSS23
LOCATION
11q14.2
LOCUSID
11098
ALIAS
SIG13,SPUVE,ZSIG13
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11098
MIM: 618376
HGNC: 14370
Ensembl: ENSG00000150687

Variants:

dbSNP: 11098
ClinVar: 11098
TCGA: ENSG00000150687
COSMIC: PRSS23

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150687ENST00000280258O95084
ENSG00000150687ENST00000527521E9PRR2
ENSG00000150687ENST00000532234E9PIB7
ENSG00000150687ENST00000533902E9PMX2

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
361893052022Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2.10
361893052022Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2.10
342708412021Exosomal microRNA-1246 from human umbilical cord mesenchymal stem cells potentiates myocardial angiogenesis in chronic heart failure.15
342708412021Exosomal microRNA-1246 from human umbilical cord mesenchymal stem cells potentiates myocardial angiogenesis in chronic heart failure.15
307690972019PRSS23 knockdown inhibits gastric tumorigenesis through EIF2 signaling.8
307690972019PRSS23 knockdown inhibits gastric tumorigenesis through EIF2 signaling.8
222919502012Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells.24
222919502012Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells.24
205322022010Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.42
205322022010Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.42

Citation

Dessen P

PRSS23 (serine protease 23)

Atlas Genet Cytogenet Oncol Haematol. 2012-06-01

Online version: http://atlasgeneticsoncology.org/gene/52748/prss23-(serine-protease-23)