RNF169 (ring finger protein 169)

2012-06-01  

Identity

HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 254225
MIM: 618650
HGNC: 26961
Ensembl: ENSG00000166439

Variants:

dbSNP: 254225
ClinVar: 254225
TCGA: ENSG00000166439
COSMIC: RNF169

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166439ENST00000299563Q8NCN4
ENSG00000166439ENST00000527301H0YEQ1

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
227428332012Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks.70
285064602017Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.24
283258772017Dual-utility NLS drives RNF169-dependent DNA damage responses.16
301043802018RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair.6
224927212012Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks.0
227338222012Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage.0
284064002017The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.0

Citation

Dessen P

RNF169 (ring finger protein 169)

Atlas Genet Cytogenet Oncol Haematol. 2012-06-01

Online version: http://atlasgeneticsoncology.org/gene/52763/rnf169-(ring-finger-protein-169)