CD200R1 (CD200 receptor 1)

2012-08-01  

Identity

HGNC
LOCATION
3q13.2
LOCUSID
ALIAS
CD200R,HCRTR2,MOX2R,OX2R
FUSION GENES

Other Information

Locus ID:

NCBI: 131450
MIM: 607546
HGNC: 24235
Ensembl: ENSG00000163606

Variants:

dbSNP: 131450
ClinVar: 131450
TCGA: ENSG00000163606
COSMIC: CD200R1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163606ENST00000295863H9KV32
ENSG00000163606ENST00000308611Q8TD46
ENSG00000163606ENST00000440122Q8TD46
ENSG00000163606ENST00000471858Q8TD46
ENSG00000163606ENST00000490004Q8TD46

Expression (GTEx)

0
1
2
3
4
5

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
129603292003Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.121
191516262009Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions.67
197865462009Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells.45
152204412004Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor.44
161770862005Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200.40
177147852008The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes.37
181644232008CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing.35
156618922005The CD200 receptor is a novel and potent regulator of murine and human mast cell function.31
180408592007CD200-CD200R regulation of microglia activation in the pathogenesis of Parkinson's disease.23
210789072010Downstream of tyrosine kinase 1 and 2 play opposing roles in CD200 receptor signaling.23

Citation

Dessen P

CD200R1 (CD200 receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-08-01

Online version: http://atlasgeneticsoncology.org/gene/52788/cd200r1-(cd200-receptor-1)