KCNG3 (potassium voltage-gated channel modifier subfamily G member 3)

2012-08-01 Affiliation

Identity

HGNC

KCNG3

LOCATION

2p21

LOCUSID

170850

ALIAS

KV10.1,KV6.3

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 170850
MIM: 606767
HGNC: 18306
Ensembl: ENSG00000171126

Variants:

dbSNP: 170850
ClinVar: 170850
TCGA: ENSG00000171126
COSMIC: KCNG3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000171126	ENST00000306078	Q8TAE7
ENSG00000171126	ENST00000394973	Q8TAE7

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Neuronal System	REACTOME	R-HSA-112316
Potassium Channels	REACTOME	R-HSA-1296071
Voltage gated Potassium channels	REACTOME	R-HSA-1296072

References

Pubmed ID	Year	Title	Citations
30718673	2019	Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership.	20
30718673	2019	Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership.	20
26530050	2015	Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival.	28
26530050	2015	Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival.	28
22204340	2012	Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy.	15
22204340	2012	Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy.	15
11852086	2002	Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1.	16
12060745	2002	Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.	58
11852086	2002	Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage-gated K(+) channel Kv2.1.	16
12060745	2002	Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.	58

Citation

Dessen P

KCNG3 (potassium voltage-gated channel modifier subfamily G member 3)

Atlas Genet Cytogenet Oncol Haematol. 2012-08-01

Online version: http://atlasgeneticsoncology.org/gene/52825/kcng3-(potassium-voltage-gated-channel-modifier-subfamily-g-member-3)