HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha)
2012-08-01 AffiliationIdentity
HGNC
LOCATION
2p23.3
LOCUSID
ALIAS
ECHA,GBP,HADH,LCEH,LCHAD,MTPA,TP-ALPHA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3030
MIM: 600890
HGNC: 4801
Ensembl: ENSG00000084754
Variants:
dbSNP: 3030
ClinVar: 3030
TCGA: ENSG00000084754
COSMIC: HADHA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37549033 | 2023 | An Autopsy Analysis of a Patient With Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Caused by Compound Heterozygous HADHA Gene Mutations. | 0 |
| 37843279 | 2023 | Zfp335 establishes eTreg lineage and neonatal immune tolerance by targeting Hadha-mediated fatty acid oxidation. | 0 |
| 37549033 | 2023 | An Autopsy Analysis of a Patient With Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Caused by Compound Heterozygous HADHA Gene Mutations. | 0 |
| 37843279 | 2023 | Zfp335 establishes eTreg lineage and neonatal immune tolerance by targeting Hadha-mediated fatty acid oxidation. | 0 |
| 34878152 | 2022 | Analysis of a family with mitochondrial trifunctional protein deficiency caused by HADHA gene mutations. | 3 |
| 36224682 | 2022 | [HADHA Inhibits the Migration and Invasion of HTR-8/SVneo Cells by Regulating PI3K/AKT Signaling Pathway]. | 0 |
| 34878152 | 2022 | Analysis of a family with mitochondrial trifunctional protein deficiency caused by HADHA gene mutations. | 3 |
| 36224682 | 2022 | [HADHA Inhibits the Migration and Invasion of HTR-8/SVneo Cells by Regulating PI3K/AKT Signaling Pathway]. | 0 |
| 32897397 | 2021 | Deep geno- and phenotyping in two consanguineous families with CMT2 reveals HADHA as an unusual disease-causing gene and an intronic variant in GDAP1 as an unusual mutation. | 1 |
| 33393495 | 2021 | Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas. | 22 |
| 34850779 | 2021 | Roles of hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha, a lipid metabolism enzyme, in Wilms tumor patients. | 1 |
| 32897397 | 2021 | Deep geno- and phenotyping in two consanguineous families with CMT2 reveals HADHA as an unusual disease-causing gene and an intronic variant in GDAP1 as an unusual mutation. | 1 |
| 33393495 | 2021 | Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas. | 22 |
| 34850779 | 2021 | Roles of hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha, a lipid metabolism enzyme, in Wilms tumor patients. | 1 |
| 31527828 | 2020 | Fatty acid beta oxidation enzyme HADHA is a novel potential therapeutic target in malignant lymphoma. | 13 |
Citation
Dessen P
HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52828/hadha-(hydroxyacyl-coa-dehydrogenase-trifunctional-multienzyme-complex-subunit-alpha)
