Identity
HGNC
LOCATION
7q36.2
LOCUSID
ALIAS
DPL1,DPPX,MRD33,VF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1804
MIM: 126141
HGNC: 3010
Ensembl: ENSG00000130226
Variants:
dbSNP: 1804
ClinVar: 1804
TCGA: ENSG00000130226
COSMIC: DPP6
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | 32451486 | |
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD | 32451486 | |
| PA449841 | haloperidol | Chemical | MultilinkAnnotation | associated | 27023437 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38381392 | 2024 | Association between DPP6 gene rs10260404 polymorphism and increased risk of sporadic amyotrophic lateral sclerosis (sALS): a meta-analysis. | 0 |
| 38381392 | 2024 | Association between DPP6 gene rs10260404 polymorphism and increased risk of sporadic amyotrophic lateral sclerosis (sALS): a meta-analysis. | 0 |
| 32701143 | 2020 | Dipeptidyl peptidase like 6 promoter methylation is a potential prognostic biomarker for pancreatic ductal adenocarcinoma. | 5 |
| 33143549 | 2020 | Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity. | 9 |
| 32701143 | 2020 | Dipeptidyl peptidase like 6 promoter methylation is a potential prognostic biomarker for pancreatic ductal adenocarcinoma. | 5 |
| 33143549 | 2020 | Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity. | 9 |
| 30874922 | 2019 | Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability. | 26 |
| 31476289 | 2019 | A novel DPP6 variant in Chinese families causes early repolarization syndrome. | 1 |
| 30874922 | 2019 | Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability. | 26 |
| 31476289 | 2019 | A novel DPP6 variant in Chinese families causes early repolarization syndrome. | 1 |
| 29474731 | 2018 | A novel mutation of dipeptidyl aminopeptidase-like protein-6 in a family with suspicious idiopathic ventricular fibrillation. | 2 |
| 29474731 | 2018 | A novel mutation of dipeptidyl aminopeptidase-like protein-6 in a family with suspicious idiopathic ventricular fibrillation. | 2 |
| 27759917 | 2017 | Implication of LRRC4C and DPP6 in neurodevelopmental disorders. | 25 |
| 27759917 | 2017 | Implication of LRRC4C and DPP6 in neurodevelopmental disorders. | 25 |
| 26681609 | 2016 | Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus. | 16 |
Citation
Dessen P
DPP6 (dipeptidyl peptidase like 6)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52851/dpp6-(dipeptidyl-peptidase-like-6)
