Identity
HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
C1orf86,FP7162
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 199990
MIM: 615183
HGNC: 26428
Ensembl: ENSG00000162585
Variants:
dbSNP: 199990
ClinVar: 199990
TCGA: ENSG00000162585
COSMIC: FAAP20
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| DNA Repair | REACTOME | R-HSA-73894 |
| Fanconi Anemia Pathway | REACTOME | R-HSA-6783310 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37620397 | 2023 | Fanconi anemia associated protein 20 (FAAP20) plays an essential role in homology-directed repair of DNA double-strand breaks. | 0 |
| 37620397 | 2023 | Fanconi anemia associated protein 20 (FAAP20) plays an essential role in homology-directed repair of DNA double-strand breaks. | 0 |
| 32763975 | 2020 | Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation. | 1 |
| 32763975 | 2020 | Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation. | 1 |
| 27232758 | 2016 | FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation. | 12 |
| 27232758 | 2016 | FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation. | 12 |
| 26318859 | 2015 | Biophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domain. | 1 |
| 26318859 | 2015 | Biophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domain. | 1 |
| 25414354 | 2014 | Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. | 6 |
| 25414354 | 2014 | Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. | 6 |
| 22343915 | 2012 | FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway. | 64 |
| 22396592 | 2012 | Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. | 57 |
| 22705371 | 2012 | A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. | 47 |
| 22343915 | 2012 | FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway. | 64 |
| 22396592 | 2012 | Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. | 57 |
Citation
Dessen P
FAAP20 (FA core complex associated protein 20)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52875/faap20-(fa-core-complex-associated-protein-20)
