TUBA1C (tubulin alpha 1c)

2012-09-01  

Identity

HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
TUBA6,bcm948
FUSION GENES

Other Information

Locus ID:

NCBI: 84790
HGNC: 20768
Ensembl: ENSG00000167553

Variants:

dbSNP: 84790
ClinVar: 84790
TCGA: ENSG00000167553
COSMIC: TUBA1C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167553ENST00000301072Q9BQE3
ENSG00000167553ENST00000541364F5H5D3
ENSG00000167553ENST00000549183F8VS66
ENSG00000167553ENST00000549818F8VRK1
ENSG00000167553ENST00000552125H0YHV2
ENSG00000167553ENST00000552448F8VRK1
ENSG00000167553ENST00000639419A0A1W2PQM2

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
ApoptosisKEGGko04210
Tight junctionKEGGko04530
Gap junctionKEGGko04540
Pathogenic Escherichia coli infectionKEGGko05130
ApoptosisKEGGhsa04210
Tight junctionKEGGhsa04530
Gap junctionKEGGhsa04540
Pathogenic Escherichia coli infectionKEGGhsa05130
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingREACTOMER-HSA-389958
Prefoldin mediated transfer of substrate to CCT/TriCREACTOMER-HSA-389957
Formation of tubulin folding intermediates by CCT/TriCREACTOMER-HSA-389960
Post-chaperonin tubulin folding pathwayREACTOMER-HSA-389977

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369415952023TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.2
369415952023TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.2
348451652022Tubulin alpha 1c promotes aerobic glycolysis and cell growth through upregulation of yes association protein expression in breast cancer.5
355137902022The oncogenic role of tubulin alpha-1c chain in human tumours.10
348451652022Tubulin alpha 1c promotes aerobic glycolysis and cell growth through upregulation of yes association protein expression in breast cancer.5
355137902022The oncogenic role of tubulin alpha-1c chain in human tumours.10
336541962021Tektin4 loss promotes triple-negative breast cancer metastasis through HDAC6-mediated tubulin deacetylation and increases sensitivity to HDAC6 inhibitor.9
345172102021TUBA1C expression promotes proliferation by regulating the cell cycle and indicates poor prognosis in glioma.14
336541962021Tektin4 loss promotes triple-negative breast cancer metastasis through HDAC6-mediated tubulin deacetylation and increases sensitivity to HDAC6 inhibitor.9
345172102021TUBA1C expression promotes proliferation by regulating the cell cycle and indicates poor prognosis in glioma.14
325991392020Circular RNA TUBA1C accelerates the progression of non-small-cell lung cancer by sponging miR-143-3p.9
325991392020Circular RNA TUBA1C accelerates the progression of non-small-cell lung cancer by sponging miR-143-3p.9
219657432011Up-regulation of 42 kDa tubulin alpha-6 chain fragment in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus.4
219657432011Up-regulation of 42 kDa tubulin alpha-6 chain fragment in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus.4

Citation

Dessen P

TUBA1C (tubulin alpha 1c)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52889/haematological-explorer/welcome