Identity
HGNC
LOCATION
6p21.2
LOCUSID
ALIAS
C6orf102,dJ1043E3.1,dJ137F1.4,dJ188D3.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 221458
MIM: 613919
HGNC: 21202
Ensembl: ENSG00000164627
Variants:
dbSNP: 221458
ClinVar: 221458
TCGA: ENSG00000164627
COSMIC: KIF6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134308647 | rosuvastatin | Chemical | ClinicalAnnotation | associated | PD | 30304062 | |
| PA443797 | Coronary Disease | Disease | ClinicalAnnotation | associated | PD | 18222353, 18222355, 20215968, 20403483, 30304062 | |
| PA444516 | Hypercholesterolemia | Disease | ClinicalAnnotation | associated | PD | 18222353, 18222355, 21458191, 30304062 | |
| PA445019 | Myocardial Infarction | Disease | ClinicalAnnotation | associated | PD | 18222353, 18222355, 20215968, 20403483, 30304062 | |
| PA448500 | atorvastatin | Chemical | ClinicalAnnotation | associated | PD | 18222353, 18222355, 20215968, 20403483, 30304062 | |
| PA451089 | pravastatin | Chemical | ClinicalAnnotation | associated | PD | 18222353, 18222355, 20215968, 20403483 | |
| PA451363 | simvastatin | Chemical | ClinicalAnnotation | associated | PD | 21458191, 30304062 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38235522 | 2024 | Motor protein Kif6 regulates cilia motility and polarity in brain ependymal cells. | 1 |
| 38235522 | 2024 | Motor protein Kif6 regulates cilia motility and polarity in brain ependymal cells. | 1 |
| 36833179 | 2023 | KIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection. | 1 |
| 36833179 | 2023 | KIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection. | 1 |
| 35342690 | 2022 | Impact of 719Trp>Arg Polymorphism of KIF 6 Gene on Contrast Induced Nephropathy in Patients Undergoing Coronary Angiography or Percutaneous Coronary Intervention. | 0 |
| 35342690 | 2022 | Impact of 719Trp>Arg Polymorphism of KIF 6 Gene on Contrast Induced Nephropathy in Patients Undergoing Coronary Angiography or Percutaneous Coronary Intervention. | 0 |
| 32867607 | 2021 | Are KIF6 and APOE polymorphisms associated with power and endurance athletes? | 2 |
| 32867607 | 2021 | Are KIF6 and APOE polymorphisms associated with power and endurance athletes? | 2 |
| 29304815 | 2018 | Association between KIF6 rs20455 polymorphism and the risk of coronary heart disease (CHD): a pooled analysis of 50 individual studies including 40,059 cases and 64,032 controls. | 1 |
| 29304815 | 2018 | Association between KIF6 rs20455 polymorphism and the risk of coronary heart disease (CHD): a pooled analysis of 50 individual studies including 40,059 cases and 64,032 controls. | 1 |
| 29295555 | 2017 | Relationship between Lipid Phenotypes, Overweight, Lipid Lowering Drug Response and KIF6 and HMG-CoA Genotypes in a Subset of the Brisighella Heart Study Population. | 7 |
| 29295555 | 2017 | Relationship between Lipid Phenotypes, Overweight, Lipid Lowering Drug Response and KIF6 and HMG-CoA Genotypes in a Subset of the Brisighella Heart Study Population. | 7 |
| 26997531 | 2016 | Investigation of KIF6 Trp719Arg gene polymorphism in a case-control study of coronary artery disease and non-fatal myocardial infarction in the Eastern Province of Saudi Arabia. | 2 |
| 26997531 | 2016 | Investigation of KIF6 Trp719Arg gene polymorphism in a case-control study of coronary artery disease and non-fatal myocardial infarction in the Eastern Province of Saudi Arabia. | 2 |
| 26443250 | 2015 | Impact of KIF6 Polymorphism rs20455 on Coronary Heart Disease Risk and Effectiveness of Statin Therapy in 100 Patients from Southern Iran. | 4 |
Citation
Dessen P
KIF6 (kinesin family member 6)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52959/kif6-(kinesin-family-member-6)
