Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 93589
MIM: 608171
HGNC: 20202
Ensembl: ENSG00000151062
Variants:
dbSNP: 93589
ClinVar: 93589
TCGA: ENSG00000151062
COSMIC: CACNA2D4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443459 | Atrial Fibrillation | Disease | Literature, MultilinkAnnotation | associated | 24727801 | ||
| PA448871 | celecoxib | Chemical | Pathway | associated | 22336956 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31834350 | 2019 | A New Zebrafish Model for CACNA2D4-Dysfunction. | 7 |
| 31834350 | 2019 | A New Zebrafish Model for CACNA2D4-Dysfunction. | 7 |
| 28726569 | 2018 | Founder Ashkenazi Jewish mutations of large deletion in the inherited retinal dystrophy genes. | 1 |
| 28726569 | 2018 | Founder Ashkenazi Jewish mutations of large deletion in the inherited retinal dystrophy genes. | 1 |
| 26560832 | 2016 | Mutations in CACNA2D4 Cause Distinctive Retinal Dysfunction in Humans. | 21 |
| 26560832 | 2016 | Mutations in CACNA2D4 Cause Distinctive Retinal Dysfunction in Humans. | 21 |
| 22488967 | 2012 | Identification of a CACNA2D4 deletion in late onset bipolar disorder patients and implications for the involvement of voltage-dependent calcium channels in psychiatric disorders. | 16 |
| 22488967 | 2012 | Identification of a CACNA2D4 deletion in late onset bipolar disorder patients and implications for the involvement of voltage-dependent calcium channels in psychiatric disorders. | 16 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 12181424 | 2002 | Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit. | 60 |
| 12181424 | 2002 | Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit. | 60 |
Citation
Dessen P
CACNA2D4 (calcium voltage-gated channel auxiliary subunit alpha2delta 4)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52976/cacna2d4-(calcium-voltage-gated-channel-auxiliary-subunit-alpha2delta-4)
