CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3)

2012-11-01  

Identity

HGNC
CELSR3
LOCATION
3p21.31
LOCUSID
1951
ALIAS
ADGRC3,CDHF11,EGFL1,FMI1,HFMI1,MEGF2,RESDA1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1951
MIM: 604264
HGNC: 3230
Ensembl: ENSG00000008300

Variants:

dbSNP: 1951
ClinVar: 1951
TCGA: ENSG00000008300
COSMIC: CELSR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008300ENST00000164024Q9NYQ7

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
385070782024CELSR3 is a prognostic marker in HNSCC and correlates with immune cell infiltration in the tumor microenvironment.0
385070782024CELSR3 is a prognostic marker in HNSCC and correlates with immune cell infiltration in the tumor microenvironment.0
372240172023The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.3
372240172023The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.3
345826972022Clinical Significance and Underlying Mechanisms of CELSR3 in Metastatic Prostate Cancer Based on Immunohistochemistry, Data Mining, and In Silico Analysis.0
349511232022CELSR3 variants are associated with febrile seizures and epilepsy with antecedent febrile seizures.6
351650642022Evaluated expression of CELSR3 in oral squamous cell carcinoma is associated with perineural invasion and poor prognosis.5
345826972022Clinical Significance and Underlying Mechanisms of CELSR3 in Metastatic Prostate Cancer Based on Immunohistochemistry, Data Mining, and In Silico Analysis.0
349511232022CELSR3 variants are associated with febrile seizures and epilepsy with antecedent febrile seizures.6
351650642022Evaluated expression of CELSR3 in oral squamous cell carcinoma is associated with perineural invasion and poor prognosis.5
338114532021Systematic expression analysis of the CELSR family reveals the importance of CELSR3 in human lung adenocarcinoma.6
338114532021Systematic expression analysis of the CELSR family reveals the importance of CELSR3 in human lung adenocarcinoma.6
302572062018De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.51
302572062018De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.51
284726522017De Novo Coding Variants Are Strongly Associated with Tourette Disorder.92

Citation

Dessen P

CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52979/celsr3-(cadherin-egf-lag-seven-pass-g-type-receptor-3)